I-C reactive protein noma i-CRP iphrotheni ekhishwa isibindi ukuphendula ukuvuvukala noma ukutheleleka emzimbeni. Kukalwa ukuze kunikezwe umbono wesimo sokuvuvukala somuntu ngesikhathi esithile.

I-C-reactive protein (CRP) iphrotheni ekhiqizwa ama-hepatocyte, okungukuthi amaseli esibindi, abese ekhishelwa egazini. Kwatholakala kuma-30s ku-plasma yeziguli ezine-pneumonia ye-pneumococcal. Ukugxila kwe-C amaprotheni asebenzayo kuyanda ngokuvuvukala noma ukutheleleka.

Kuwuphawu lokuqala lwempendulo yokuvuvukala. Lokhu kungenxa yokuthi ukukhiqizwa kwayo ngesibindi nokukhululwa kwayo emgudwini wegazi kwanda phakathi namahora angu-4 kuya kwangu-6 ngemva kwesiqalo, kufinyelela ekugxilweni kwayo okuphezulu kakhulu ngemva kwamahora angu-36 kuya kwangu-50. Ukukhiqizwa kwayo ngokuvamile kwandulela ubuhlungu, umkhuhlane kanye nokunye ukubonakaliswa kwemitholampilo yokuvuvukala.

Kwezinye izifo, ukwenyuka kwamaprotheni asebenzayo e-C kungaba kukhulu kakhulu. Kunjalo, isibonelo:

• izifo ezibangelwa amagciwane noma fungal;
• izifo ezivuthayo: i-rheumatoid arthritis noma i-spondyloarthritis, ukugaya ukudla njenge-Crohn's disease, i-dermatological efana ne-psoriasis;
• umdlavuza njenge-lymphoma noma i-carcinoma;
• i-infarction ye-myocardial;
• ukuhlukumezeka.

Ingakhula kodwa ibe ngaphansi kwezifo ezibangelwa amagciwane, i-lupus, i-ulcerative colitis, i-leukemia noma ezimeni ezivuvukalayo ezihambisana nesibindi.

Ukuhlolwa kwe-CRP kungaqinisekisa ngokuthembekile ukuba khona kokuvuvukala. Kodwa-ke, akucacile kakhulu, okusho ukuthi ayinikezi ulwazi mayelana nemvelo yalokho okubangela ukuvuvukala.

Iphrotheni esebenzayo ye-C inguphawu lokuvuvukala, ukuhlolwa kwayo kwenza kube nokwenzeka ukuhlola isimo sokuvuvukala sesiguli. Umthamo ungacelwa ezimweni ezahlukahlukene:

• kwenza kube nokwenzeka ukuqinisekisa noma ukukhipha ubukhona bokuvuvukala kanye / noma ukutheleleka;
• kwenza kube nokwenzeka ukuqapha ukusebenza kokwelashwa;
• ukuhlolwa kwe-C-reactive protein kungase kucelwe kumuntu osanda kuhlinzwa futhi okusolakala ukuthi unezinkinga kuye;
• ingasetshenziswa futhi ukuxilonga nokuqapha isimo sesifo esingapheli sokuvuvukala, kanye nokuqapha ukwelashwa kwaso.

Umthamo wenziwa ngokuhlolwa kwegazi. Akudingekile ukuba ube esiswini esingenalutho. Qaphela, nokho, ukuthatha imithi ethile efana nemithi engeyona i-steroidal eqeda ukuvuvukala noma i-estrogens (iphilisi lokuvimbela inzalo, i-contraceptive implant, i-IUD, ama-hormone athatha indawo yokunqamuka kokuya esikhathini, njll.) kungenza umphumela ube ongelona iqiniso. Kubalulekile ukwazisa udokotela kanye nelabhorethri yokuhlaziya, ukuphuza noma yimiphi imithi (enqunyiwe noma e-counter-the-counter) noma umkhiqizo wezempilo wemvelo (isithasiselo sokudla, imithi ye-herbal, amafutha abalulekile, njll.).

Okunye ukuhlolwa kokuhlola ukuvuvukala kungenziwa ngokuhambisana nokuhlolwa kwe-CRP. Leli izinga lokugcwala kwamangqamuzana abomvu egazi. Lokhu futhi kunikeza ulwazi oluthakazelisayo mayelana nesimo sokuvuvukala somuntu. Kodwa-ke, ukuhlushwa kwe-C amaprotheni asebenzayo kuhlotshaniswa kakhulu ngokuhamba kwesikhathi nokuvuvukala. Ngempela, ukugxila kwayo kukhula ngokushesha ngemva kwe-trigger futhi kuncipha ngokushesha lapho ukwelashwa kusebenza. Izinga le-sedimentation lingahlala liphazamisekile isikhathi eside.

Uma umphumela ophezulu

Umphumela ophezulu usho ukuba khona kokuvuvukala emzimbeni. Lokhu kuvuvukala kungabangelwa ukutheleleka (ibhaktheriya noma ukhunta), isifo sokuvuvukala, umdlavuza, njll. Abantu abakhuluphele ngokweqile nabesifazane abakhulelwe nabo bavame ukuba namazinga aphezulu amaprotheni e-C-reactive angaphezu kwavamile.

Ngokuvamile, sithola:

• ukugxila kwe-10-40 mg / L, uma kwenzeka ukuvuvukala okumaphakathi noma izifo ezibangelwa amagciwane;
• ukugxila kwe-50-200 mg / L, ekuvuvukeni okukhulu noma izifo ezibangelwa amagciwane;
• ukukhuphuka okuncane, phakathi kuka-3 no-10 mg / L, kungatholakala nasezimeni zokukhuluphala, ukubhema, isifo sikashukela, umfutho wegazi ophakeme, indlela yokuphila yokuhlala, ukwelapha ama-hormone, ukuphazamiseka kokulala, ukukhathala okungapheli kanye nokucindezeleka.

Uma umphumela uphakeme, udokotela uzodinga ukwenza ezinye izivivinyo nokuhlolwa ukuze athole imbangela yalokhu kuvuvukala. Ukwanda kwawo kuwuphawu oluyisixwayiso kodokotela. Lezi kuyodingeka ukuthi zivumelane nokuqapha nokwelashwa kwesiguli ngendlela efanele.

Uma umphumela ophansi

Kudingeka umphumela ophansi.

Ukwelashwa kokuvuvukala kuzoxhomeka ngembangela yaso (isifo esingelapheki, ukutheleleka, umdlavuza, njll.). Uma ukwelashwa kokuvuvukala kuphumelela, izinga le-protein C esebenzayo lizobuyela esimweni esivamile ngokushesha.