Ufuna ukwenza izinqumo ezihlakaniphile? Bese udle njalo, ugweme ama-surges ashukela egazini! Ukuqinisekiswa kwalo mthetho olula kwavela eSweden: ngokusekelwe emiphumeleni yocwaningo lwabo lwakamuva, ososayensi baseSalgrenska Academy eNyuvesi yaseGothenburg bayeluleka ukuthi bangenzi izinqumo ngesisu esingenalutho, ngoba uma ulambile, i-hormone ghrelin ikhiqizwa. , okwenza izinqumo zakho zibe ngamawala. Khonamanjalo, ukuthatheka kuwuphawu olubalulekile lwezifo eziningi ze-neuropsychiatric kanye nokuphazamiseka kokuziphatha, okuhlanganisa nokuziphatha kokudla. Imiphumela yocwaningo eshicilelwe kujenali I-Neuropsychopharmacology, lapho ingosi ethi "Neurotechnology.rf" ibhekisela kuyo.
I-ghrelin ebizwa ngokuthi "i-hormone yendlala" iqala ukukhiqizwa esiswini lapho i-glucose yegazi yehla ibe yinani elibalulekile (futhi izinguquko ezinjalo kumazinga kashukela zikhuthazwa, ikakhulukazi, ngokusetshenziswa kabi koshukela namanye ama-carbohydrate acwengekile kanye nokunganakwa okunempilo. ukudla okulula). Ososayensi baseSweden ocwaningweni lwamagundane (funda kabanzi ngakho ngezansi) ngokokuqala ngqá bakwazi ukukhombisa ukuthi lapho i-ghrelin eyengeziwe egazini, ukukhetha kwakho kuba okungalawuleki. Ukukhetha ngokuxhamazela kuwukungakwazi ukwenqaba ukwanelisa isifiso sesikhashana, ngisho noma kungenanzuzo noma kuyingozi ngobuqotho. Umuntu okhetha ukwanelisa izifiso zakhe ngokushesha, nakuba ukulinda kuzomzuzisa ngokwengeziwe, ubonakala njengokuxhamazela, okusho ikhono eliphansi lokwenza izinqumo ezihluzekile.
"Imiphumela yethu ibonise ukuthi ngisho nomphumela omncane ovimbelayo we-ghrelin endaweni ye-ventral tegmental - ingxenye yobuchopho eyingxenye ebalulekile yesistimu yokuvuza - yayanele ukwenza amagundane abe nomfutho. Into eyinhloko ukuthi lapho siyeka ukujova i-hormone, "ukucabangela" kwezinqumo kubuyele kumagundane, "kusho uKarolina Skibiska, umbhali oyinhloko womsebenzi.
Impulsivity iwuphawu lwezinkinga eziningi ze-neuropsychiatric kanye nokuziphatha, ezifana ne-attention deficit hyperactivity disorder (ADHD), i-Obsessive-compulsive disorder (OCD), ukuphazamiseka kwe-autism spectrum, ukuluthwa izidakamizwa kanye nokuphazamiseka kokudla. Ucwaningo lubonise ukuthi ukunyuka kwamazinga e-ghrelin kubangele izinguquko zesikhathi eside ezakhini zofuzo ezishintsha i-dopamine "yenjabulo" kanye nama-enzyme ayo ahlobene, okuyisici se-ADHD ne-OCD.
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Ososayensi eSalgrenska Academy banqume kanjani ukuthi amazinga aphezulu e-ghrelin akhipha amagundane ngaphandle kwenhloso yawo yokuqala yokuthola inani nomvuzo owengeziwe? Ososayensi bavuselela amagundane ngoshukela lapho enza isenzo esithile ngendlela efanele. Isibonelo, bacindezele i-lever lapho isignali "yaphambili" ikhala, noma abazange bayicindezele uma kuvela isignali "yemisa". Ekukhetheni kwabo, “basizwa” amasignali ngendlela yokubaneka kokukhanya noma umsindo othile, okwakwenza kwacaca ukuthi yiziphi izenzo okufanele bazenze ngaleso sikhathi ukuze bathole umvuzo wabo.
Ukucindezela i-lever lapho isignali enqatshelwe ivuliwe kwakubhekwa njengophawu lokungacabangi. Abacwaningi bathola ukuthi amagundane anikezwe imithamo ye-intracerebral ye-ghrelin, elingisa isisusa sokudla, kungenzeka ukuthi acindezele i-lever ngaphandle kokulinda isignali yokuyeka, naphezu kweqiniso lokuthi lokhu kubangele ukuthi balahlekelwe umvuzo.