Phakathi nokuhlolwa okude, kwakungenzeka ukuthuthukisa indlela entsha ephumelelayo yokuthatha izidakamizwa ezinemiphumela yokulwa nokuvuvukala kanye ne-anti-cancer. Kuyaziwa ukuthi noma yimuphi umuthi, ngisho obizayo, unohlu lwemiphumela engathandeki kanye nemiphumela engemihle ewubangelayo lapho uthathwa ngomlomo.
Kuze kube namuhla, umsebenzi onzima uyaqhubeka wokwenza imithi emisha enomphumela omubi omncane emzimbeni. Umqondo uwukuthi umuthi kufanele usebenze kuphela ezicutshini ezigulayo, ezilimele izifo nezitho. Ngesikhathi esifanayo, izitho ezinempilo kufanele zihlale ziphilile ngaphandle kokuchayeka kumakhemikhali. Ukuze kuncishiswe ukusatshalaliswa kwalezi zinto ezinhlelweni zomzimba ezinempilo, kwanqunywa ukuthi kuncishiswe umthamo womuthi owodwa noma omunye.
Ezimweni zaselabhorethri, ososayensi basakwazi ukuqinisekisa ukuthi umuthi usakazeka endaweni ethile kuphela, kuyilapho ezinye izitho zomzimba zingahlupheki. Kodwa-ke, ukusetshenziswa kwalezi zindlela kwandisa izindleko zezidakamizwa izikhathi eziningana, okungamukeleki ngokuphelele ekusetshenzisweni kwazo emisebenzini yansuku zonke.
Noma kunjalo, inkinga yaxazululwa ngenxa yomsebenzi ohlangene wochwepheshe baseMelika nabaseRussia baseNovosibirsk University. Indlela entsha yabonakala ingabizi kakhulu futhi iphumelela kakhulu maqondana nezicubu nezitho ezingenampilo.
Ikuphi inkinga ngemithi yesimanje?
Njengoba sekufakazelwe kakade, umthamo othile wezinto ezisebenzayo zemithi awusetshenziselwa injongo ehlosiwe, ewela ezithweni nezicubu ezingadingi ukungenelela kwezokwelapha.
Imithi eminingi esetshenziswayo ayimuncwa ngokuphelele umgudu wamathumbu. Enye inkinga evimbela ukungena kwezinto ezidingekayo esitokisini ukukhetha kwe-membrane yeseli. Ngokuvamile, ukuze kunqobe le nkinga, iziguli kudingeka zandise imithamo yezidakamizwa ukuze okungenani ezinye zazo zifike lapho ziya khona. Lesi simo singaxazululwa ngosizo lwemijovo ehambisa umuthi ezithweni ezifunwayo kanye nezicubu, ngokudlula umgudu wokugaya ukudla. Nokho, le ndlela ayihlali iphephile futhi inzima ekusetshenzisweni kwansuku zonke kwasekhaya.
Isixazululo sitholakele. Manje ama-clathrates anesibopho sokudlula esitokisini ngolwelwesi lwaso.
Imvelo ngokwayo yasiza ukuthola le ndlela yokuxazulula inkinga. UProfesa weNovosibirsk Institute of Organic Chemistry, isazi sezinto eziphilayo uTatyana Tolstikova wachaza ukuthi kunezinhlanganisela ezikhethekile zamaprotheni emzimbeni ezisiza izinto ezingancibilikisiwe ukuba zingene esithweni esifunwayo. Lawa maprotheni, abizwa ngokuthi abathutha, awakwazi nje ukuhambisa izinto emzimbeni, kodwa futhi angena ngaphakathi kweseli, ephula ulwelwesi.
Ngosizo lwala maprotheni, ososayensi baseNyuvesi yaseNovosibirsk bazama ukunyakaza kwama-molecule ezidakamizwa. Ngemva kokuhlolwa okuningana, kwacaca ukuthi i-glycyrrhizic acid, engahlanganiswa kusuka empandeni ye-licorice, iyindlela engcono kakhulu yokuthutha izinto ezidingekayo.
Le nhlanganisela inezici eziyingqayizivele. Ngokuxhuma ama-molecule angu-4 ale asidi, kutholakala uhlaka, olungenalutho ngaphakathi. Ngaphakathi kwalolu hlaka, kwavela umqondo wokubeka ama-molecule omuthi owawufunwa. Izinto ezikwazi ukwenza lesi sakhiwo zibizwa ngokuthi ama-clathrates ku-chemistry.
Imiphumela yokuhlolwa kwezidakamizwa
Ukuze kuthuthukiswe nokucwaninga, ososayensi abaningi babehileleke kulo msebenzi, kuhlanganise nalabo abavela ku-IHTTMC kanye ne-IHKG yegatsha laseSiberia le-Academy of Sciences. Bahlonze ubuchwepheshe obuthile bokukhiqiza ama-clathrates futhi baxazulula inkinga yokungena kwabo ngodonga lwe-cell membrane. Ithiyori yesenzo sale nto iye yahlolwa ekuhlolweni ngezilwane. Ukuhlola kubonise ukuthi le ndlela ngempela inomphumela omncane ezinhlelweni zomzimba ezinempilo, ithinta kuphela amangqamuzana angenampilo. Lokhu kwenza ukwelashwa kuphumelele ngangokunokwenzeka futhi kukuvumela ukuba unciphise kakhulu umthamo wemithi, okungenakwenzeka njalo ngezindlela zendabuko zokwelapha. Esinye isici esihle sale ndlela ukuthi umthelela omubi ohlelweni lokugaya uyancipha kakhulu.
Amalungiselelo asekelwe empandeni ye-licorice kubikezelwa ukuthi azosakazeka emikhakheni eminingi yezokwelapha. Ngokwesibonelo, ukusetshenziswa embonweni amalungiselelo aqukethe lutein. Inomphumela omuhle ku-retina, kodwa umzimba awuwutholi kahle. Uma isegobolondweni le-conveyor, umphumela womuthi uzothuthuka izikhathi ezingamakhulu.