Ukutheleleka kwamafungal kuvame ukuvela ngokungalingani okulula kwama-microorganisms ngokwemvelo emzimbeni.

Empeleni ikholoniwe yizinhlobo eziningi zesikhunta nama-bacterium, isikhathi esiningi esingenabungozi futhi esibaluleke kakhulu ekusebenzeni kahle komzimba.

Kodwa-ke, kungenzeka ukuthi ezinye zalezi zikhunta ziyanda futhi zibe yi-pathogenic, noma ukuthi isikhunta "sangaphandle", esidluliselwa ngokwesilwane yisilwane, sidala ukutheleleka. Izinhlobo ezingama-200-400 zesikhunta zingadala izifo kubantu⁵.

Kodwa-ke, isikhunta esikhona emvelweni singangcolisa nabantu, ngokwesibonelo:

• nge-inoculation, ngesikhathi sokulimala isibonelo (okuholela ku-sporotrichosis noma i-chromomycosis, njll.);
• ngokuhogela isikhunta (i-histoplasmosis, i-apergillosis, njll.);
• ngokuxhumana nomuntu onegciwane (candidiasis, izikelemu, njll.);
• ngokuxhumana nesilwane esinegciwane.