Ngokokunye ukulinganisa, isifo samathambo sithinta abantu abadala abangafika ku-1% emhlabeni wonke, kodwa asebekhulile bayizisulu ezivame kakhulu. I-Rheumatoid arthritis ichazwa njengesifo esingelapheki esibonakala ngokuvuvukala kwamalunga kanye nezakhiwo ezihlobene nomzimba, okuholela ekukhubazekeni komzimba. I-etiology eqondile (imbangela yesifo) ayaziwa, kodwa kucatshangwa ukuthi isifo sokuzivikela komzimba. Ososayensi bakholelwa ukuthi abukho ubufakazi besayensi bokuthi noma yikuphi ukudla noma izakhi ezithile, ngaphandle kwama-acids abalulekile, kusiza noma kulimaza abantu abane-arthritis ye-rheumatoid. Ososayensi ngokuvamile batusa ukudla okunomsoco futhi bagcizelela isidingo sokudla okwanele ama-kilojoule, amaprotheni, ne-calcium. Abantu abane-arthritis ye-rheumatoid banikezwa izincomo ezilandelayo: Kuyadingeka ukusebenzisa i-1-2 g yamaprotheni ngekhilogremu ngayinye yesisindo somzimba (ukunxephezela ukulahleka kwamaprotheni ngesikhathi sezinqubo zokuvuvukala). Udinga ukuthatha i-folic acid eyengeziwe ukuze uvimbele imiphumela emibi ye-methotrexate. I-Methotrexate iyisithako esilwa ne-metabolic esivimba ukusabela okudingekayo ekukhiqizeni izandulela ku-DNA synthesis. I-folic acid ikhishwa kule enzyme i-dihydrofolate reductase, futhi i-folic acid yamahhala iyakhululwa. Umthamo ophansi we-methotrexate uvame ukusetshenziswa ekwelapheni i-rheumatoid arthritis ukucindezela amasosha omzimba. Ngenxa yokuthi alikho ikhambi eliqashelwayo le-rheumatoid arthritis, ukwelashwa kwamanje kwalesi sifo kunqunyelwe ngokuyinhloko ukukhululeka kwezimpawu ngemithi. Ezinye izidakamizwa zisetshenziswa kuphela njengezidambisi zobuhlungu, ezinye njengezidakamizwa ezilwa nokuvuvukala. Kukhona okuthiwa imithi eyisisekelo yokwelapha i-rheumatoid arthritis, esetshenziselwa ukwehlisa ukuhamba kwalesi sifo. I-Corticosteroids, eyaziwa nangokuthi i-glucocorticoids, njenge-urbazone ne-prednisone, isetshenziswa ekwelapheni i-rheumatoid arthritis ngoba iphikisana nokuvuvukala futhi icindezela amasosha omzimba. Lawa ma-ejenti anamandla abeka iziguli engcupheni eyengeziwe ye-osteoporosis. Abantu abathola ukwelashwa kwe-steroid isikhathi eside kufanele bathintane nodokotela wezokudla ukuze bathole iseluleko mayelana nokudla kwe-calcium, ukuthathwa kwe-vitamin D, nokuzivocavoca ukuze bavimbele ukukhumuzeka kwamathambo. Ukwenqatshwa kwemikhiqizo ethile Kunobufakazi bokuthi abantu abane-arthritis ye-rheumatoid bathola ukukhululeka ngezinguquko zokudla. Izimbangela zezimpawu ezibikwa kakhulu zihlanganisa amaprotheni obisi, ummbila, ukolweni, izithelo ezisawolintshi, amaqanda, inyama ebomvu, ushukela, amafutha, usawoti, i-caffeine, nezitshalo ze-nightshade ezifana namazambane nesitshalo seqanda. izitshalo ezisekelwe ekudleni Mayelana neqhaza lamabhaktheriya amathumbu ekuthuthukisweni kwesifo samathambo, abantu abaphethwe yiso banenani elikhulu lamasosha omzimba e-Proteus mirabilis, uma kuqhathaniswa nabantu abanempilo kanye nabantu abaphethwe ezinye izifo. Abadla imifino banamazinga aphansi kakhulu amasosha omzimba, ahlotshaniswa nokuncishiswa kwesifo okusesilinganisweni. Kungacatshangwa ukuthi ukudla okusekelwe esitshalweni kunomphumela omuhle ebukhoneni bamagciwane amathumbu afana ne-Proteus mirabilis, kanye nokusabela komzimba kumagciwane anjalo. Ukunciphisa isisindo Ngenxa yokuthi ukukhuluphala ngokweqile kubeka ingcindezi eyengeziwe emalungeni, ukuncipha kwesisindo ngokudla kungaba ukwelashwa kwesifo samathambo. Imiphumela ye-chain chain fatty acids Ubufakazi obuvela ocwaningweni oluningi bubonisa ukuthi ukuxhaphazwa kokudla okunamafutha acid kunomphumela onenzuzo ezinqubweni zokuvuvukala. I-prostaglandin metabolism incike ohlotsheni nenani lamafutha acid ekudleni, futhi izinguquko ekugxilweni kwe-prostaglandin zingathinta ukuphendula komzimba komzimba. Ukudla okunamafutha amaningi e-polyunsaturated namafutha aphansi agcwele, kanye nokusetshenziswa kwansuku zonke kwe-eicosapentaenoic acid, kuholela ekunyamaleni kwalolu phawu lwe-rheumatological njengokuqina kwasekuseni kanye nokuncipha kwenani lamalunga agulayo; ukwenqaba ukudla okunjalo kuholela ezimpawu zokuhoxa. Abadla imifino bangakhuphula ukudla kwabo omega-3 ngokusebenzisa imbewu yefilakisi nokunye ukudla kwezitshalo. Indima yezinye imisoco Olunye ucwaningo luye lwabonisa ukuthi abantu abanesifo samathambo babhebhetheka ngenxa yokungatholi amavithamini nemisoco eyanele. Iziguli ezinesifo samathambo zikuthola kunzima ukupheka nokudla ngenxa yobuhlungu bamalunga ezandla. Ukunganyakazi nokukhuluphala nakho kuyinkinga. Ngakho-ke, abantu abanesifo samathambo kufanele bafune iseluleko kochwepheshe mayelana nokudla okunomsoco, ukulungiswa kokudla, nokuncipha kwesisindo. Iziguli ezinesifo samathambo maningi amathuba okuba zibulawe isifo senhliziyo nemithambo yegazi. Amazinga aphezulu e-homocysteine ahlotshaniswa ne-rheumatoid arthritis. Isimo esifanayo sibonwa ngisho nakubantu abangayithathi i-methotrexate, ethinta okuqukethwe kwe-folate emzimbeni. Njengoba ukudla kwemifino kuphumelela ekulweni nesifo senhliziyo, kungasiza futhi abantu abaphethwe yi-rheumatoid arthritis. Ngokungangabazeki, ukudla okuphezulu ekudleni kwezitshalo okuphezulu ku-folate kungaba yisinqumo esihle kubantu abanamazinga aphezulu e-homocysteine egazini labo. Okwamanje asinayo imibono eqondile evela emphakathini wesayensi ngomthelela wokudla imifino ku-rheumatoid arthritis, kodwa kunengqondo ukuthi abantu abagulayo bazame ukudla kwemifino noma imifino futhi babone ukuthi kubasiza kanjani. Kunoma yikuphi, ukudla kwemifino kunomphumela onenzuzo empilweni futhi ukuhlolwa okunjalo ngeke kube okungaphezu kwamandla.
2022-11-11