La i-syphilis inezigaba ezi-3 kanye nesikhathi sokubambezeleka. Izigaba zokugcwala okuyisisekelo okuyisisekelo, sekondari kanye nezasekuqaleni kubhekwa njengokutheleleka. Inkundla ngayinye ine izimpawu ehlukile.

Isigaba sokuqala

Izimpawu ziqala ukuvela ezinsukwini ezi-3 kuya kwezingama-90 ngemuva kokutheleleka, kepha imvamisa amasonto ama-3.

• Ekuqaleni, ukutheleleka kuqala ukubonakala kwe- inkinobho ebomvu ;
• Lapho-ke amabhaktheriya ayanda futhi ekugcineni akha elilodwa noma amaningi izilonda ezingenabuhlungu endaweni yokutheleleka, imvamisa esithweni sangasese, sendunu noma somphimbo. Lesi silonda sibizwa ngokuthi i-chancre chancre. Iyabonakala kupipi, kodwa ifihlwe kalula esithweni sangasese noma endunu, ikakhulukazi njengoba ingenabuhlungu. Abantu abaningi abanegciwane bakhulisa ishashana elilodwa kuphela, kepha abanye bakhula ngaphezu kweyodwa;

• Isilonda sigcina sizixazululele sodwa kungakapheli inyanga eyodwa kuya kwezi-1. Uma ingazange yelashwe, noma kunjalo, lokhu akusho ukuthi ukutheleleka kuyelapheka.

Isigaba sesibili

Uma ingalashwa, ugcunsula luyaqhubeka. Emasontweni amabili kuya kwayishumi emva kokuqala kwezilonda, kuvela lezi zimpawu ezilandelayo:

• Umkhuhlane, ukukhathala, ikhanda nobuhlungu bemisipha;
• Ukulahleka kwezinwele (alopecia);
• Ukubomvu nokuqubuka ezingxenyeni zomlomo nezesikhumba, kufaka phakathi izintende zezandla naphansi kwamathe ezinyawo;
• Ukuvuvukala igenge;
• Ukuvuvukala kwe-uvea (uveitis), ukunikezwa kwegazi esweni, noma i-retina (retinitis).

Lezi zimpawu zingaphela zodwa, kodwa akusho ukuthi ukutheleleka kuyelapheka. Zingavela futhi zivele ngezikhathi ezithile, izinyanga noma ngisho neminyaka.

Isikhathi se-latency

Ngemuva kweminyaka engaba mibili, i- i-syphilis ingena esimeni sokubambezeleka, isikhathi lapho kungekho zimpawu ezivela khona. Noma kunjalo, ukutheleleka kusengakhula. Lesi sikhathi singahlala unyaka owodwa kuya eminyakeni engama-1.

Isigaba semfundo ephakeme

Uma ishiywe ingalashwa, u-15% kuya ku-30% wabantu abatheleleke ngayo i-syphilis uphethwe yizimpawu ezimbi kakhulu kwesinye isikhathi okungaholela kuzo ukufa :

• Ugcunsula wenhliziyo (ukuvuvukala kwe-aorta, i-aneurysm noma i-aortic stenosis, njll.);
• Ugcunsula wemithambo yegazi (isifo sohlangothi, meningitis, ukungezwa, ukuphazamiseka okubukwayo, ikhanda, isiyezi, ushintsho ebuntwini, ukuwohloka komqondo, njll.);
• Ugcunsula azalwa naso. I-Treponema idluliselwa kumama onegciwane nge-placenta futhi izoholela ekuphuphumeni kwezisu, ukufa kwezinsana. Iningi lezingane ezisanda kuzalwa ezithintekayo ngeke zibe nazimpawu lapho zizalwa, kepha zizovela kungakapheli izinyanga ezintathu kuya kwezine;
• Izikhungo : ukubhujiswa kwezicubu zanoma yisiphi isitho.