Okuqukethwe
Ukushiswa yilanga nokuzivikela komzimba: kwenzekani ngenkathi ulele olwandle
Izinto ezihambisanayo
Kungani ukugeza ilanga kube yingozi? Yibaphi ososayensi abasha abazositshela?
Manje kunemigqa ephelele yokuvikela okuxazulula inkinga yemiphumela eyingozi yemisebe ye-UV esikhumbeni. Kepha ungayivimbela kanjani imiphumela yokushisa kwayo okukhulu? Kuyaziwa ukuthi elangeni izingqimba ezingenhla zesikhumba zingashisa zifike ku- + 40 ° C. Ngaphezu kwalokho, kulesi simo “esishisa ngokweqile”, ziyaqhubeka nokuba ngamahora amaningi ngisho nangemva kokushiswa yilanga. Kungani ukucindezela okushisayo kuyingozi kangaka?
Siyini isikhumba futhi kungani sisidinga
Ngokombono we-biology, isikhumba siyisicubu sokuvimbela esihlukanisa imvelo yangaphakathi yomzimba womuntu nengaphandle. Ngokuya ngalokhu, yisikhumba, njengezinye izicubu emzimbeni wethu, esihlangabezana nemiphumela yemvelo. Imvelo yale miphumela yehlukile: imishini, amakhemikhali, izinga lokushisa, njll. Lokho ukuthi, ukuze sisebenze njengesithiyo, isikhumba kufanele ngasikhathi sinye siqine ngokomshini, simelane namakhemikhali nangokomzimba, kufanele sisivikele ngempumelelo emisebeni ye-ultraviolet nakwizifo ( amagciwane, amabhaktheriya)… Emva kokuxazulula zonke lezi zinkinga, imvelo idale ukwakheka okunengqondo kakhulu futhi okuhle.
Isisekelo sesikhumba sethu luhlobo olukhethekile lwamaseli - ama-keratinocyte. Umjikelezo wokuphila kwalawa maseli ukulandelana kokuguqulwa kweseli eliphilayo kuya esikalini se-keratinized. Bakha ukwakheka okunemigqa eminingi, ehlelwe ngendlela eyinkimbinkimbi yamaseli axhumene ngokuqinile - i-epithelium. Inani lalezi zingqimba linquma amandla womshini wesikhumba. Isendlalelo esingezansi amaseli angavuthiwe avela kuwo wonke amaseli angaphezulu kwezendlalelo ezingaphansi. Ingqimba engenhla yesikhumba yakhiwa izingqimba eziningi zamaseli asengaphili, ase-keratinized asevele engaphili. Yibo abathatha imithelela yomshini, yomzimba neyamakhemikhali, ngaleyo ndlela bavikele amangqamuzana aphilayo kubo.
Amaseli wokuvikela amagciwane nezimila
Kodwa-ke, kusenamaseli amaningi ezivakashi esikhunjeni. Isibonelo, ama-immunocyte. Ziyakhula futhi zikhule emnkantsheni wethambo, bese kuthi, ukuhamba emzimbeni, nazo zingene esikhunjeni. Indawo okuhlala kuyo la maseli ngaphambi kokuxoshwa esikhunjeni ibonakala ngokushisa okungaguquguquki nokwakheka kwamakhemikhali. Lapha (esikhumbeni) ama-immunocyte aphoqeleka ukuthi ahlanganyele namaseli esikhumba bonke "ubunzima" bempilo emaphethelweni. Lapho kuvezwa amazinga okushisa aphezulu naphansi, imisebe yelanga, isimo sokusebenza kwamaseli anjalo sihlolwa ngokujulile.
Phakathi kwamaseli omzimba esikhumba kukhona uhlobo olukhethekile lwamaseli - amangqamuzana angokwemvelo okubulala (amaseli we-NK). Benza umsebenzi obaluleke kakhulu - bayaqaphela futhi babulale amaseli anegciwane futhi aguqulwe (isimila). Ukuphazamiseka kokusebenza okujwayelekile kwalawa maseli kuholela emiphumeleni emibi: ukubuyela emuva kwe-herpes, ama-neoplasms esikhumba (ama-papillomas), njll. Kwavela ukuthi ngisho nokushintshashintsha kokushisa okulula kungathinta umsebenzi wamaseli we-NK ("defender cell"). Ucwaningo oluningi lukhombisile ukuthi ukwanda kwesikhashana esifushane kwezinga lokushisa kuya ku- + 39 ° C kunciphisa kakhulu ikhono lamaseli we-NK ukubona nokucekela phansi amaseli akhokhelwe.
Yingakho kunzima ukugcizelela ukuthi kungenzeka yini ukugcina imisebenzi yamaseli we-NK yesikhumba sethu, azithola esezimweni ezinjalo.
Ukutholwa okwenziwe eSt
Ngo-2013, iphephabhuku laseMelika i-International immunopharmacology lachaza izakhiwo ze-Allostatin® peptide, ezatholwa iqembu lososayensi baseSt. Petersburg State University. I-Allostatin® isishukumisi esikhethiwe samaseli we-NK. Ososayensi bathole ukuthi phambi kwama-Allostatin®, amaseli we-NK athola futhi abhubhise amaseli akhonjwe izikhathi eziphindwe ka-5.
Ngakho-ke, i-Allostatin® ingaba ukusekelwa okujulile kwamaseli we-NK ngaphansi kwamazinga okushisa ashintshayo. Umkhiqizo wokuqala wezimonyo osuselwa ku-Allostatin® bekuyi-hydrogel yokunakekelwa kwesikhumba nezindebe - i-Allomedin®.
Izindlela zanamuhla zokugcina isikhumba esinempilo zifaka phakathi ukulandela imithetho yokuqothuka ngemuva. Kuwumkhuba ojwayelekile ukusebenzisa ukhilimu oqukethe uvithamini E ukubuyisa isikhumba ngemuva kokuvezwa yimisebe ye-UV.
Ukunciphisa imiphumela eyingozi yokushisa okuphezulu esikhumbeni, faka ijeli le-Allomedin® esimisweni sakho esijwayelekile sangemva kokunakekelwa. Ijeli kufanele lisetshenziswe ngemuva kokugeza, ezindaweni zesikhumba ezivezwa ukukhanya kwelanga okukhulu (ngokweqile). Akunzima ukuwachaza: okokuqala, lezi zihlala ziyizindawo ezivulekile zomzimba (ubuso), futhi ngaphandle kwalokho, isikhumba esinjalo siyaqhubeka "nokushisa" ngisho namahora ambalwa ngemuva kokuvezwa yilanga. Ijeli ye-peptide i-Allomedin® ipholisa ngokushesha isikhumba, iqeda izinhlungu futhi ibuyise umsebenzi wamaseli "wokuvikela" ngaphandle kokushiya noma iyiphi insalela. Khumbula ukuthi i-tan efanele iyisiqinisekiso sobuhle nobusha eminyakeni ezayo.
* Uma izimpawu ze-herpes sezivele, sebenzisa i-Allomedin® ngaso sonke isikhathi lapho uzizwa ubabaza, uluma futhi uvutha.
Imininingwane Yokuxhumana:
Inkampani ye-Biotechnological "Allopharm"
+7 (812) 320-55-42,
Izimo kungenzeka. Xhumana nochwepheshe.