I-OCD izoba ngenxa ye-a ukuntuleka kwe-serotonin ebuchosheni. Izidakamizwa ezisetshenziswa kakhulu zandisa inani le-serotonin kuma-synapses (ukuhlangana phakathi kwama-neurons amabili) ngokuvimbela ukuphinda kuthathwe kwakamuva. Le mithi ibizwa ngokuthi i-serotonin reuptake inhibitors. Benza lula ukudlula komlayezo othuthumelayo.

Ama-antidepressants akhethiwe amakhulu e-serotonin reuptake inhibitor (SSRI) anqunyiwe yilawa:

• I-Fluvoxamine (Floxyfral® / Luvox®)
• I-Fluoxetine (Prozac®)
• I-Sertraline (Zoloft ®)
• I-Paroxetine (Deroxat® / Paxil®)
• I-Escitalopram (Seroplex®/Lexapro®)
• I-Citalopram (Seropram®/Celexa®)

Ziyasebenza ku-OCD ngemva kwamasonto ambalwa okwelashwa. Ukwelashwa ngokuvamile kuthatha iminyaka eminingana. Esimeni sokuvela kabusha kokuphazamiseka, umthamo unganyuswa noma kuzanywe i-molecule entsha. Iziguli ezingaphezu kwesigamu zizobona isimo sazo sithuthuka ngenxa yokwelashwa kwezidakamizwa okushintshile.

I-Clomipramine (Anafranil®), engeyelinye ikilasi lama-antidepressants, ama-tricyclic antidepressants, futhi aqala ukuboniswa ukuthi ayasebenza ku-OCD, angase futhi anqunywe.¹⁶. Ngokuvamile isetshenziswa njengomugqa wesibili, uma izidakamizwa zokuqala zingaboniswanga ukuthi ziyasebenza, ngoba imiphumela yayo emibi ingaba ephawulekayo.

Imithamo enqunyelwe i-OCD imvamisa iphakeme kuneyokwelapha ukudangala. Uma ukwelashwa kubonakala kungasebenzi, udokotela wezifo zengqondo kufanele athintwe ngoba amanye ama-molecule afana ne-lithium noma i-buspirone (Buspar®) angazanywa.

Ama-anxiolytics ekilasi le-benzodiazepine angase abekwe ukuze kuncishiswe ukukhathazeka. Isibonelo, i-clonazepam (i-Rivotril®) ibonise ukusebenza kahle okuthile ekwelapheni i-OCD. Nokho, kuye kwabikwa izingozi zokuguquguquka kwemizwelo, ukucasuka kanye nemicabango yokuzibulala.¹⁷.

Ukuvuselela ugesi, okusetshenziswe ku-Parkinson's disease, kuye kwaba nemiphumela ethile ku-OCD eqinile noma engalapheki.¹⁸. Ukuvuselela ubuchopho obujulile (i-DBS) kuhilela ukufaka ama-electrode ebuchosheni futhi ukuwaxhuma kusivuseleli esiletha amandla kagesi. Le ndlela yokuhlasela isahlolwa¹⁹. Ukuvuselela kancane okunamandla kazibuthe (ukuthumela i-pulse kazibuthe engenabuhlungu ngekhoyili) kunganikezwa.

Izinkinga ezihlobene ne-OCD nazo zidinga ukulawulwa.

Ukwelashwa kwe-obsessive-compulsive disorder ngokuvamile kuhilela ukwelashwa kokuziphatha kanye nokucabanga. Lokhu kwelashwa kuhloswe ukunciphisa ukukhathazeka okuhlobene nokuthatheka ngokweqile kanye nokunciphisa ukucindezelwa okubangelwa yilokhu kukhathazeka. Amaseshini angaqukatha izivivinyo ezingokoqobo, umuntu azithole ebhekene nezimo azesabayo, ukuphumula noma ukudlala indima ethile.

Izidakamizwa kanye ne-psychotherapies ingahlanganiswa futhi iboniswe ukuthi iyasebenza. Eqinisweni, izingxenye ezimbili kwezintathu zeziguli ezelashwayo zizobona ukuphazamiseka kwazo kuncipha. Inhlanganisela yalokhu okubili ngokuvamile inikezwa ngokuqondile uma kwenzeka kuba nokuphazamiseka okukhulu noma ngemva kokwehluleka komuthi owodwa.

Kwesinye isikhathi lesi sifo simelana nokwelashwa. Lokhu ngokuvamile kusebenza kubantu abanezifo ezinzima kakhulu futhi abanenkinga ye-bipolar kanye nokuphazamiseka kwemikhuba yokudla. Ukulaliswa esibhedlela kungase kudingeke.