Le i-reflux yesisu kubhekisa ekukhuphukeni kwengxenye yokuqukethwe kwesisu kuyeisophagus (umgudu oxhumanisa umlomo nesisu). Isisu sikhiqiza ujusi wesisu, okuyizinto ezine-asidi kakhulu ezisiza ekugayeni ukudla. Kodwa-ke, ulwelwesi lwe-esophagus alwakhelwanga ukumelana nobuncwane bokuqukethwe esiswini. Ngakho-ke i-Reflux ibangela ukuvuvukala komphimbo, okuholela ekushisweni nasekucasukeni. Ngokuhamba kwesikhathi, kungalimala umphimbo. Qaphela ukuthi izinga eliphansi le-reflux livamile futhi alibalulekanga, futhi lokhu kubhekiswa njenge-reflux yomzimba (ejwayelekile).

Izimbangela

Kubantu abaningi abanayo, i-reflux ibangelwa ukungasebenzi kahle kwe- i-sphincter ephansi ye-esophageal. Le sphincter iyindandatho yemisipha etholakala lapho kuhlangana khona umphimbo nesisu. Imvamisa, iyaqina, ivimbela okuqukethwe esiswini ukuthi kungagudluki kuye phezulu, kuvuleke kuphela ukuvumela ukudla okufakiwe kudlule futhi ngaleyo ndlela kusebenze njenge-valve evikelayo.

Esimweni se-reflux, i-sphincter ivula ngezikhathi ezingalungile bese ivumela i- iziphuzo zesisu kwesisu. Abantu abahlushwa i-reflux bavame ukubuyiswa kabusha kwe-asidi ngemuva kokudla noma ebusuku. Lesi simo sokuvuselelwa sivame kakhulu ezinganeni, ngoba i-sphincter yazo ayivuthiwe.

Isifo se-reflux se-gastroesophageal naso singaxhunywa i-hernia yokuzalwa. Kulokhu, ingxenye ephezulu yesisu (etholakala lapho kuhlangana khona umphimbo) “iyakhuphuka” ne-esophagus in the cage cage ngokuvulwa kwe-diaphragm (i-oral orifice). 

Kodwa-ke, i-hiatus hernia nesifo se-reflux se-gastroesophageal asihambisani, futhi i-hiatus hernia ayihlali ihlotshaniswa ne-reflux.

Ukuvama

ECanada, kulinganiselwa ukuthi amaphesenti ayi-10 kuye kwangama-30 wabantu angakhathazwa yiziqephu ezithile ze Reflux isisu⁷. Futhi ama-4% abantu baseCanada bazoba ne-reflux yansuku zonke ngama-30% kanye ngesonto (13).

Ucwaningo lwaseMelika lukhombisa ukuthi abantu abangama-44% banesifo se-reflux se-gastroesophageal okungenani kanye ngenyanga ().

Ukuphinda uvuseleleke kuvame kakhulu ezinganeni, kepha akuhlali kungenxa yesifo se-reflux se-gastroesophageal. Ochwepheshe balinganisela ukuthi izingane ezingama-25% zineqiniso Reflux⁸. Ifinyelela ekugcineni kwayo ezungeze iminyaka engu-4 izinyanga⁹.

Evolution

Kubantu abadala abaningi abathintekile, izimpawu ze-reflux azilapheki. Ukwelashwa kuvame ukuhlinzeka ukukhululeka okuphelele, kepha kwesikhashana, kwezimpawu. Azisilaphi lesi sifo.

Ezinganeni, i-reflux ivame ukuhamba phakathi kwezinyanga eziyisithupha kuya kwezingu-6 lapho ingane ikhula.

Izinkinga

Ukuvezwa isikhathi eside kwesisu ezintweni ezinesisu se-gastric kungadala:

• Ukuvuvukala (okophagite), enezilonda ezingaphezulu noma ezijulile zomhosha obhekene nazoizilonda (noma izilonda) odongeni lwesisu, ezihlelwe ngezigaba ezi-4, ngokuya ngenombolo yazo, ukujula kwazo, kanye nobukhulu bazo;
• lokhu kuvuvukala noma isilonda kungadala ukubola kwesisu ;
• ukunciphisa ububanzi bomphimbo (i-peptic stenosis), okudala ubunzima bokugwinya nobuhlungu ngesikhathi sokugwinya;
• un Isisu sikaBarrett. Kungukushintshwa kwamaseli asodongeni lwesisu ngamaseli ajwayele ukuvela emathunjini. Lokhu kufakwa esikhundleni kungenxa "yokuhlaselwa" okuphindaphindwayo kwesisu esiswini. Akuhambisani nanoma yiziphi izimpawu ezithile, kepha kungatholwa nge-endoscopy ngoba umbala ojwayelekile ompunga-obomvana wezicubu zomzimba uthatha umbala ovuvukile obomvana-obomvana. Isimomondiya sikaBarrett sikubeka engcupheni yezilonda futhi, okubaluleke kakhulu, umdlavuza wesimila.

Isifo se-reflux se-gastroesophageal naso singaholela ezinkingeni ezikude¹⁰ :

• ukukhwehlela okungapheli 
• izwi elihoshozelayo
• laryngospasme
• umdlavuza we-esophagus noma i-larynx uma kwenzeka i-reflux engalawulwa futhi engaqashwa

Ukubonisana nini?

Esimeni ngasinye kulezi ezingezansi, kuyalulekwa ukuthi bonana nodokotela.

• Ukuzwa okushisayo nokuvuselelwa kwe-asidi kaningana ngesonto.
• Izimpawu ze-reflux ziphazamisa ukulala.
• Izimpawu zibuyela ngokushesha lapho uyeka ukuthatha imishanguzo yokulwa nezidakamizwa.
• Izimpawu sezihlale isikhathi esingaphezu konyaka futhi azikaze zihlolwe udokotela.
• Kunezimpawu ezethusayo (bheka isigaba sesifo sokushisa).