Umthamo we-creatinine, igazi (i-serum creatinine) noma umchamo (i-creatininuria) isetshenziswa ngakolunye uhlangothi ukukala ukusebenza kwezinso kanye nokuxilonga ukuwohloka okungenzeka kokusebenza kwezinso.

Ukuhlaziywa kwe-Creatinine nakho kwenziwa ukuze kuqinisekiswe ukusebenza kwemisipha, lokhu okulandelayo kungumphumela wenqubo yokuwohloka kwemisipha. Ngakho-ke, uma kukhulu ukuminyana kwemisipha, umthamo we-creatinine uzoba mkhulu. 

Isifinyezo

Yini i-creatinine?

Ukuhlaziywa kwe-Creatinine

Imiphi imiphumela ongayilindela ekuhlolweni kwe-creatinine?

Izinga eliphezulu le-creatinine

Izinga le-creatinine eliphansi

La i-creatinine ngakho-ke kuvela ku ukwephulwa kwe-creatine, ngokwawo synthesized by the isibindi futhi agcinwe phakathi imisipha lapho idlala indima ebalulekile ekukhiqizeni amandla. Ukusetshenziswa kwemisipha kwe-creatine kukhiqiza udoti, okuphawuleka kakhulu kuwo i-creatinine. Lokhu kuthwalwa yigazi, lihlungwe yizinso bese liphuma emchamweni. Ngakho-ke, ukuqhathanisa izinga le-creatinine egazini nenani le-creatinine elikhishwe emchameni kwenza kube lula ukuhlola umsebenzi wezinso.

Qaphela ukuthi ukuhlushwa kwe-creatinine kuyahlukahluka kuye ngesisindo somzimba womuntu. Ngakho, amadoda ngokuvamile anezinga eliphezulu le-creatinine egazini kunabesifazane.

Kwenziwa kanjani ukuhlolwa kwegazi kwe-creatinine?

Ukuhlolwa kwegazi iqukethe ukuhlolwa kwegazi le-venous, ngokuvamile endaweni yokugoba kwendololwane.

Njengoba izinga le-creatinine egazini lihlobene nokusebenza kwemisipha, kutuswa ukuba uyeke noma yikuphi ukuvivinya umzimba okukhandlayo phakathi namahora angu-48 ngaphambi kokuhlolwa. Ngaphezu kwalokho, ngenxa yokuthi inyama ebomvu inothile nge-creatine, kunconywa ukuthi inciphise ukusetshenziswa kwayo ibe ngaphansi kwamagremu angama-200 amahora angama-24 ngaphambi kokuhlolwa, noma ungayidli nhlobo. Ukusetshenziswa kweziphuzo noma imikhiqizo ye-diuretic kufanele kugwenywe ngayizolo nangosuku lokuhlolwa.

Udokotela wakho angase futhi akucele ukuthi uyeke ukuphuza imithi ethile ngaphambi kokuhlolwa.

Kwenziwa kanjani ukuhlolwa komchamo we-creatinine?

Ukususwa kwe-creatinine yomchamo, okulinganisa inani le-creatinine elikhishwa yizinso egazini, lilinganiselwa kumthamo ophelele womchamo okhiqizwa emahoreni angu-24.

Kulokhu, umchamo uqoqwa esitsheni esisodwa esinikezwe le njongo enikezwe abasebenzi bezokwelapha. Umchamo kufanele ugcinwe esiqandisini.

Ukuhlushwa okujwayelekile kwe-creatinine egazini kuphakathi 6 kanye ne-12 mg / l (ama-milligram ilitha ngalinye) kubantu naphakathi 4 kanye ne-10 mg / l kwabesifazane. Lawa manani angahluka kuye ngomthombo.

Isibalo esivamile sokuvuzwa kwe-creatinine yomchamo siphakathi 107 kanye ne-139 ml / min (amamililitha ngomzuzu) emadodeni angaphansi kweminyaka engama-40, naphakathi 87 kanye ne-107 ml / min kwabesifazane abangaphansi kweminyaka engama-40.

Ukugcwala okuphezulu kwe-creatinine egazini kungaba uphawu:

• ukungasebenzi kahle kwezinso, njengokuhluleka kwezinso
• ukuba khona kwetshe lezinso
• i-ischemia, uma kwenzeka ukunciphisa ukunikezwa kwegazi ezinso
• ukutheleleka
• isifo sezinso
• umdlavuza wezinso ezimweni ezimbi kakhulu
• yokumelwa yinhliziyo
• ukukhathala ngokomzimba
• kwamanzi emzimbeni
• ukulimala kwemisipha
• noma ngisho nangokwengeziwe, kusukela ku-rhabdomyolysis (ukubhujiswa kwezicubu ze-striated muscle)

Ukuhlushwa okuphezulu kwe-creatinine egazini kuhlotshaniswa nokucaciswa okuphansi komchamo. Yingakho izimbangela ze-creatinine clearance ephansi yomchamo zifana nalezi ezixoxwe ngenhla.

Izinga eliphansi le-creatinine egazini lingase libe uphawu:

• imisipha ephansi ebangelwa i-muscular dystrophy noma nje ehlobene neminyaka
• ukulimala kwesibindi
• noma ukukhulelwa

Ukususwa kwe-creatinine enkulu kungase kube uphawu lwe-carbon monoxide poisoning, noma ngisho ne-hypothyroidism.