Izimpawu zomzimba nezengqondo ezihlotshaniswa nokusetshenziswa kwe-cocaine kungenxa yemiphumela yayo enamandla evuselelayo ohlelweni lwezinzwa, lwenhliziyo, lwenhliziyo, lwamathumbu kanye nokuphefumula komzimba.

• Izimpawu ezikhethekile ezihlobene nokusetshenziswa kwe-cocaine:

  - umuzwa wenjabulo;

  - isimo sokuzindla;

  - ukukhuphuka kwamandla;

  - ukusheshisa inkulumo;

  - ukunciphisa isidingo sokulala nokudla;

  - ngezinye izikhathi kulula ukwenza imisebenzi yengqondo neyomzimba, kodwa ngokulahlekelwa ukwahlulela;

  - ukwanda kwenhliziyo;

  - ukwanda komfutho wegazi;

  - ukuphefumula ngokushesha;

  – umlomo owomile.

Izingozi zezempilo zokusetshenziswa isikhathi eside

• Izingozi zomthengi:

  - ukungezwani okuthile;

  - ukulahlekelwa ukudla kanye nesisindo;

  - ama-hallucinations;

  - ukuqwasha;

  - ukulimala kwamangqamuzana esibindi namaphaphu;

  - izinkinga zepheshana lokuphefumula (ukucinana kwamakhala okungamahlalakhona, ukulimala okungapheli ku-cartilage we-septum yamakhala, ukulahlekelwa umuzwa wokuhogela, ubunzima bokugwinya);

  - Izinkinga zenhliziyo nemithambo yegazi (umfutho wegazi ophakeme, ukushaya kwenhliziyo okungajwayelekile, i-fibrillation ye-ventricular, ukudlikizeka, ukuqhanyelwa, ukuboshwa kwenhliziyo nokufa okungazelelwe, kanye nomthamo owodwa wama-20 mg);

  - izinkinga zamaphaphu (ubuhlungu besifuba, ukuboshwa kokuphefumula);

  - izinkinga zezinzwa (ikhanda elibuhlungu, ukujabula, ukucindezeleka okujulile, imicabango yokuzibulala);

  - izinkinga emathunjini (ubuhlungu besisu, isicanucanu);

  - i-hepatitis C ekushintsheni izinaliti;

  - Ukutheleleka nge-HIV (abasebenzisi be-cocaine maningi amathuba okuba bahlanganyele ekuziphatheni okuyingozi, njengokwabelana ngezinaliti nokuba nocansi olungavikelekile).

  I-cocaine nayo ingabangela izinkinga ezihlobene nezinkinga ezithile zempilo uma umuntu esevele ehlushwa kuzo (ikakhulukazi: isifo sesibindi, i-Tourette syndrome, i-hyperthyroidism).

  Kufanele futhi sikhulume ukuthi inhlanganisela i-cocaine-utshwala iyimbangela evame kakhulu yokufa okuhlobene nezidakamizwa.

• Izingozi ku-fetus:

  - ukufa (ukukhipha isisu okuzenzakalelayo);

  - ukuzalwa ngaphambi kwesikhathi;

  - okungavamile ngokomzimba;

  - isisindo nobude ngaphansi kokujwayelekile;

  - isikhathi eside: ukuphazamiseka kokulala nokuziphatha.

• Izingozi enganeni encela ibele (i-cocaine idlulela obisini lwebele):

  - ukudlikizela;

  - ukukhuphuka komfutho wegazi;

  - ukwanda kwenhliziyo;

  - izinkinga zokuphefumula;

  - ukucasuka okungavamile.

• Imiphumela engemihle yokuhoxa:

  - ukucindezeleka, ukozela ngokweqile, ukukhathala, ikhanda elibuhlungu, indlala, ukucasuka kanye nobunzima bokugxila;

  - kwezinye izimo, ukuzama ukuzibulala, i-paranoia kanye nokulahlekelwa ukuxhumana namaqiniso (i-psychotic delirium).