Ayikho indlela eyaziwa ngodokotela yokuvimbela isifo sikaParkinson. Nokho, nakhu okubonisa ucwaningo.

Amadoda adla iziphuzo ezine-caffeine emaphakathi (ikhofi, itiye, i-cola) (1 kuya kwezingu-4 izinkomishi ngosuku) angase azuze emthelela wokuvikela ngokumelene nesifo sika-Parkinson, ngokusho kocwaningo lweqembu oluvela kumaphiko amakhulu1,2,11,12. Ucwaningo olwenziwa kubantu baseShayina lwabonisa umphumela ofanayo34. Ngakolunye uhlangothi, kwabesifazane, umphumela wokuvikela awuzange uboniswe ngokucacile. Noma kunjalo, ucwaningo lweqembu leminyaka engu-18 lwathola ukuthi ingozi yesifo sika-Parkinson yehla kubasebenzisi bekhofi abangazange bathathe i-hormone replacement therapy ngesikhathi sokunqamuka kokuya esikhathini. Ngokuphambene, ukuthatha i-hormone replacement therapy kanye ne-caffeine ndawonye kungandisa ingozi.13

Ukuphuza inkomishi eyodwa kuya kwezine zetiye eliluhlaza ngosuku nakho kubonakala kuvimbela isifo sikaParkinson, umphumela okukholakala ukuthi ubangelwa, okungenani ngokwengxenye, ukuba khona kwe-caffeine etiyeni eliluhlaza. Kwabesilisa, imithamo ephumelela kakhulu isukela ku-400 mg kuya ku-2,5 g we-caffeine ngosuku, noma okungenani izinkomishi ezi-5 zetiye eliluhlaza ngosuku.

Ngaphezu kwalokho, abantu abayimilutha kagwayi mancane amathuba okuba babe nesifo sikaParkinson. Ngokocwaningo olwanyatheliswa ngo-2012, le ngozi iyancipha ngo-56% kwababhemayo, uma kuqhathaniswa nalabo abangakaze babheme. I-Nicotine ingashukumisa ukukhululwa kwe-dopamine, ngaleyo ndlela inxephezele ukushoda kwe-dopamine okutholakala ezigulini. Kodwa-ke, le nzuzo ayinasisindo esikhulu uma iqhathaniswa nazo zonke izifo ezibangelwa ukubhema, ikakhulukazi izinhlobo eziningana zomdlavuza.

Ukuhlaziywa kwemeta eminingana kubonisa ukuthi ibuprofen ingase ihlotshaniswe nengozi encishisiwe yesifo sikaParkinson. Idatha yezinye izidakamizwa ezingezona ukuvuvukala (ama-NSAID) iyangqubuzana, okunye ukuhlaziya kwe-meta kuthola ukuthi ama-NSAID ahlotshaniswa nengozi encishisiwe yesifo kuyilapho abanye bebika ukuthi akukho ukuhlangana okubalulekile.