Njengamanje, akukho ukwelashwa kwe-prophylactic (okuvimbela) futhi ukugoma komuntu kusacwaningwa.

Ukuvimbela i-leishmaniasis kuhlanganisa:

• Ukugqoka izingubo zokumboza ezindaweni ezisengozini.
• Ukulwa nama-sandflies kanye nokucekelwa phansi kwama-parasite reservoirs.
• Ukusetshenziswa kwezidakamizwa (izidakamizwa ezixosha omiyane) ngaphakathi nasezindlini ezizungezile (izindonga zamatshe, amahhoko, ama-henhouses, igumbi lokulahla udoti, njll.).
• Ukusetshenziswa kwamanethi omiyane afakwe umuthi wokuxosha. Qaphela, amanye amanetha omiyane angase angasebenzi, ngoba i-sandfly, encane ngosayizi, ingadlula nge-mesh.
• Ukomiswa kwamaxhaphozi, njengamanye ama-pathologies asakazwa omiyane (umalaleveva, chikungunya, njll.).
• Ukugoma ezinjeni (“I-Canileish", Amalabhorethri e-Virbac).
• Ukwelashwa kwendawo ezihlala kuyo izinja (indlwana) ngezinto ezixosha inja kanye nokugqokwa kohlobo lwekhola “I-Scalibor»Ifakwe isibulala-zinambuzane esinamandla futhi esinomphumela wokuxosha.