Okuqukethwe
Isifo se-Kawasaki: kuyini?
Isifo se-Kawasaki ukuvuvukala kanye necrosis yezindonga zemithambo yemithambo nemithambo ehambisana nokungasebenzi kahle kwamasosha omzimba (febrile systemic vascularity).
Ngezinye izikhathi kuhilela imithambo yenhliziyo. Ngaphezu kwalokho, ngaphandle kokwelashwa, kungaba yinkimbinkimbi yi-coronary aneurysms, ku-25 kuya ku-30% yamacala. Futhi kuyimbangela evame kakhulu yesifo senhliziyo esitholwe ezinganeni emazweni athuthukile, futhi ingase ibe yingozi yenhliziyo ye-ischemic kubantu abadala.
Ifinyelela kubani? Izinsana nezingane ezineminyaka ephakathi kwengu-1 nengu-8 ngokuvamile zihlushwa isifo i-Kawasaki.
Ingabe ukutheleleka kwe-SARS-CoV-2 kungaholela ekubonakalisweni komtholampilo okubi kakhulu ezinganeni, okufana nezimpawu ezibonwa isifo se-Kawasaki? Ekupheleni kuka-Ephreli 2020, izinsizakalo zezingane e-UK, France nase-US zibike inani elincane lamacala ezingane ezilaliswe esibhedlela ezine-systemic inflammatory disease, izimpawu zazo ezisikhumbuza lesi sifo esingavamile sokuvuvukala. Ukuvela kwalezi zimpawu zomtholampilo kanye nokuxhumana kwazo ne-Covid-19 kuphakamisa imibuzo. Cishe izingane ezingamashumi ayisithupha zaziphethwe yikho eFrance, ngesikhathi zivalelwe zixhumene ne-coronavirus.
Kepha-ke ingabe kukhona ukuxhumana phakathi kwe-SARS-CoV-2 coronavirus kanye nesifo se-Kawasaki? “Kunokuhlangana okunamandla phakathi kokuqala kwalezi zigameko kanye nobhubhane lwe-Covid-19, kodwa akuzona zonke iziguli ezihlolwe ukuthi zinalo. Ngakho-ke imibuzo eminingana isalokhu ingaphendulekile futhi iyisihloko sokuqhubeka nophenyo eminyangweni yezingane, ”kuphetha u-Inserm. Ngakho-ke lesi sixhumanisi sidinga ukucutshungulwa kabanzi, noma ngabe njengamanje, uhulumeni ukholelwa ukuthi isifo se-Kawasaki sibonakala singase sibe esinye isethulo se-Covid-19. Lokhu kokugcina kuphawula, nokho, ukuthi "ukuqala kwayo kungathandwa ukutheleleka ngegciwane okungaqondile". Ngempela, "i-Covid-19 iyisifo esibangelwa amagciwane (njengabanye), ngakho-ke kusobala ukuthi izingane, ezilandela ukuthintana ne-Covid-19, zithole isifo se-Kawasaki ngokuhamba kwesikhathi, njengoba kwenzeka kwezinye izifo ezibangelwa amagciwane," uyaqinisekisa, nokho ekhumbula ukubaluleka kokuxhumana nodokotela wakhe uma kwenzeka ukungabaza. Noma kunjalo, isibhedlela i-Necker sithokozile yiqiniso lokuthi zonke izingane zithole ukwelashwa okujwayelekile kwalesi sifo, futhi zonke zasabela kahle, ngokuthuthuka okusheshayo kwezimpawu zomtholampilo futhi ikakhulukazi ukululama kokusebenza kahle kwenhliziyo. . Ngasikhathi sinye, kuzobalwa kwabantu kuzwelonke kuzosungulwa yisikhungo sePublic Health France.
Yiziphi izimbangela zesifo se-Kawasaki?
Izimbangela eziqondile zalesi sifo esingatheleleki akwaziwa, kodwa kungenzeka ukuthi sibangelwa ukutheleleka ngegciwane noma amagciwane ezinganeni. I-Inserm yazisa ukuthi “ukuqala kwayo kuye kwahlotshaniswa nezinhlobo ezimbalwa zezifo ezibangelwa amagciwane, futhi ikakhulukazi namagciwane okuphefumula noma amagciwane. "Kungaba yindlela yokusabela ngemuva kobhubhane lwegciwane, ukuqhubeka kwengxenye yakhe u-Olivier Véran, uNgqongqoshe Wezempilo.
Lesi sifo esibonwa ezinganeni ezithintekile kucatshangwa ukuthi siwumphumela wokusebenza ngokweqile kwamasosha omzimba kulandela ukungenwa elinye lala magciwane. “
Yiziphi izimpawu zesifo se-Kawasaki?
Isifo se-Kawasaki sihlukaniswa ngomkhuhlane omude, ukuqubuka, i-conjunctivitis, ukuvuvukala kolwelwesi lwamafinyila kanye ne-lymphadenopathy. Futhi, ukubonakaliswa kokuqala yi-myocarditis eyingozi ngokuhluleka kwenhliziyo, i-arrhythmias, i-endocarditis ne-pericarditis. I-coronary artery aneurysms ingakheka. Izicubu ezingaphandle kwemithambo nazo zingavuvukala, okuhlanganisa umgudu wokuphefumula ongaphezulu, amanyikwe, ama-bile ducts, izinso, ulwelwesi lwamafinyila nama-lymph nodes.
“Le nkulumo yomtholampilo ivusa isifo sikaKawasaki. Ukuseshwa kokutheleleka nge-Covid-19 kutholakale kunempilo, kungaba nge-PCR noma nge-serology (i-antibody assay), isigaba sokuqala sokutheleleka asizange sibonakale ezimweni eziningi, ngaphandle kwesixhumanisi singasungulwa kulesi sigaba Covid ”, ikhombisa ukusungulwa. Okungavamile, lesi sifo esiyingozi sibonakala ngokuvuvukala kolwelwesi lwemithambo yegazi, ikakhulukazi leyo yenhliziyo (imithambo yenhliziyo). Sihlasela kakhulu izingane ezincane ngaphambi kweminyaka engu-5. Nakuba kuye kwabikwa amacala emhlabeni wonke, lesi sifo sivame kakhulu kubantu base-Asia, kusho i-Inserm endaweni yokwaziswa.
Ngokwezibalo zayo, eYurophu, izingane ezingu-9 kweziyikhulu zibika lesi sifo unyaka ngamunye, nenani eliphakeme laminyaka yonke ebusika nasentwasahlobo. Ngokusho kwesizindalwazi se-Orphanet, lesi sifo siqala ngomkhuhlane ongapheli, obuye uhambisane nezinye izimpawu ezijwayelekile: ukuvuvukala kwezandla nezinyawo, ukuqubuka, i-conjunctivitis, izindebe ezibomvu eziqhekekile nolimi olubomvu oluvuvukele ("ulimi olusajingijolo"). ama-lymph nodes entanyeni, noma ukucasuka. “Naphezu kocwaningo oluningi, akukho ukuhlolwa kokuxilonga okutholakalayo, futhi ukuxilongwa kwayo kusekelwe ezimisweni zomtholampilo ngemva kokungabandakanyi ezinye izifo ezinomkhuhlane ophezulu futhi oqhubekayo,” usho kanje.
Isifo se-Kawasaki: nini sokukhathazeka
Ezinye izingane ezinezinhlobo ezingaphezu kwe-atypical zesifo, ezinomonakalo omkhulu enhliziyweni (ukuvuvukala kwemisipha yenhliziyo) kunesimo sayo sakudala. Laba bakamuva baphinde baphathwe yisiphepho se-cytokine, njengezinhlobo ezinzima ze-Covid-19. Ekugcineni, izingane zivele zivele ngokushesha ngenxa yokuhluleka kwenhliziyo ngenxa yesifo sokuvuvukala kwe-myocardium (izicubu zemisipha yenhliziyo), ezinezimpawu ezincane noma ezingenazo nhlobo zesifo.
Yiziphi izindlela zokwelapha isifo se-Kawasaki?
Ngenxa yokwelashwa kusenesikhathi ngama-immunoglobulins (abuye abizwe ngokuthi amasosha omzimba), iningi leziguli lilulama ngokushesha futhi aligcini noma yiziphi izimpawu.
Ukuxilongwa okusheshayo kusalokhu kubalulekile ngoba kunengozi yokulimala emithanjeni ye-coronary. “Lo monakalo wenzeka enganeni eyodwa kweziyisihlanu enganakiwe. Ezinganeni eziningi, zisezincane futhi azihlali isikhathi eside. Ngokuphambene, baphikelela isikhathi eside kwabanye. Kulokhu, izindonga ze-coronary arteries ziba buthaka futhi zenze ama-aneurysms (ukuvuvukala kwendawo yodonga lomkhumbi wegazi olunomumo webhaluni ", kuphawula inhlangano" AboutKidsHealth ".