I-Hyperlymphocytosis ukwanda okungavamile kwenani lama-lymphocyte egazini. Kungase kube nzima uma kuhlangene ngesikhathi sokutheleleka ngegciwane noma okungapheli, ikakhulukazi uma kuhlotshaniswa ne-hemopathy eyingozi. I-Hyperlymphocytosis itholakala ngesikhathi sokuhlolwa kwegazi okuhlukahlukene. Futhi ukwelashwa kuncike imbangela.

Incazelo

I-Hyperlymphocytosis ukwanda okungavamile kwenani lama-lymphocyte egazini ngokuvamile angaphansi kuka-4000 lymphocyte i-cubic millimeter ngayinye kubantu abadala.

Ama-lymphocyte ama-leukocyte (ngamanye amazwi amangqamuzana amhlophe egazi) adlala indima ebalulekile ohlelweni lokuzivikela komzimba. Kunezinhlobo ezintathu zama-lymphocyte:

• Ama-lymphocyte B: lapho ethintana ne-antigen, akhiqiza amasosha omzimba athile kule nto engaphandle komzimba
• T lymphocyte: Amanye abhubhisa ama-antigen namangqamuzana angenwe yileli gciwane ngokunamathisela olwelwesini lwamangqamuzana awo ukuze awajove ngama-enzyme anobuthi, amanye asiza ama-B lymphocyte enze amasosha omzimba, kanti amanye akhiqiza izinto ezivimbela ukusabela komzimba.
• Ama-lymphocyte e-Natural Killer: anomsebenzi wemvelo we-cytotoxic ozivumela ukuthi zibhubhise ngokuzenzakalelayo amaseli angenwe ngamagciwane noma amaseli omdlavuza.

izinhlobo

I-Hyperlymphocytosis ingaba:

• I-acute uma ihlangana ngesikhathi sokutheleleka ngegciwane;
• Okungapheli (okuhlala ngaphezu kwezinyanga ezingu-2) ikakhulukazi uma kuhlotshaniswa ne-hemopathy eyingozi;

Izimbangela

I-acute (noma esebenzayo) i-hyperlymphocytosis ingabangelwa:

• Ukutheleleka ngegciwane (i-mumps, inkukhu noma i-mononucleosis, i-hepatitis, i-rubella, ukutheleleka nge-HIV, isifo sikaCarl Smith);
• Ezinye izifo ezibangelwa amagciwane, njengesifo sofuba noma ukukhwehlela, zingaba nomphumela ofanayo;
• Ukuthatha imithi ethile;
• Ukugoma ;
• Izifo ze-endocrine;
• Izifo ze-Autoimmune;
• Ukubhema;
• Ukucindezeleka: i-hyperlymphocytosis ibonakala ezigulini ezivezwe ezenzakalweni ezihlukahlukene ezibuhlungu, zokuhlinzwa noma zenhliziyo, noma ngesikhathi sokuzikhandla okukhulu ngokomzimba (ukubeletha);
• Ukususwa ngokuhlinzwa kobende.

I-hyperlymphocytosis engapheli ingabangelwa:

• i-leukemia, ikakhulukazi i-lymphoid leukemia;
• I-Lymphomas;
• Ukuvuvukala okungapheli, ikakhulukazi uhlelo lokugaya ukudla (isifo sikaCrohn).

kwesifo

I-Hyperlymphocytosis itholakala ngesikhathi sokuhlolwa kwegazi okuhlukahlukene:

• Isibalo segazi esiphelele: ukuhlolwa kwebhayoloji okwenza kube nokwenzeka ukulinganisa izakhi zamangqamuzana ajikeleza egazini (amangqamuzana amhlophe egazi, amangqamuzana egazi abomvu namaplatelet) kanye nokunquma ingxenye yamangqamuzana egazi amhlophe ahlukene (ikakhulukazi ama-lymphocyte);
• Lapho isibalo segazi sibonisa ukwanda kwenani lama-lymphocyte, udokotela uhlola isampula yegazi ngaphansi kwesibonakhulu ukuze anqume ukuminyana kwama-lymphocyte. I-heterogeneity enkulu ku-morphology ye-lymphocytes ngokuvamile ibonisa i-mononucleosis syndrome, futhi ukuba khona kwamangqamuzana angavuthiwe kuyisici se-leukemia noma i-lymphomas ethile;
• Ekugcineni, ukuhlolwa kwegazi okwengeziwe kungaphinda kubone uhlobo oluthile lwe-lymphocyte (T, B, NK) olukhushulwa ukusiza ukucacisa imbangela.

Abantu abathintekayo

I-Hyperlymphocytosis ithinta zombili izingane ezihlala zisebenza futhi zidlula, kanye nabantu abadala okungaba okwesikhashana noma okungamahlalakhona (bese kuyimvelaphi eyingozi kuma-50% wamacala).

Ngokwayo, ukwanda kwenani lama-lymphocyte ngokuvamile akubangeli izimpawu. Kodwa-ke, kubantu abane-lymphoma kanye ne-leukemia ethile, i-hyperlymphocytosis ingabangela:

• Imfiva ;
• Ukujuluka ebusuku;
• Ukwehla kwesisindo.

Ukwelashwa kwe-hyperlymphocytosis kuncike kumbangela yayo, okuhlanganisa:

• Ukwelashwa okubonakalayo kwezifo eziningi zegciwane ezibangela i-hyperlymphocytosis eyingozi;
• Ukwelashwa ngama-antibiotic ngezifo ezibangelwa amagciwane;
• I-Chemotherapy, noma ngezinye izikhathi i-stem cell transplantation, ukwelapha i-leukemia;
• Ukususwa kwembangela (ukucindezeleka, ukubhema)

Ukuvimbela i-acute hyperlymphocytosis kuhilela ukuvimbela izifo ezibangelwa amagciwane namagciwane ezingadala lesi sifo:

• Ukugoma, ikakhulukazi ngokumelene nomvukuzane, i-rubella, isifo sofuba noma ukukhwehlela;
• Ukusetshenziswa njalo kwamakhondomu ngesikhathi socansi ukuvikela i-HIV.

Ngakolunye uhlangothi, asikho isilinganiso sokuvimbela i-hyperlymphocytosis engapheli.