Okuqukethwe
I-amino acid esabalele kakhulu. Kuyinto eyinhloko yeprotheyini ebizwa nge-collagen. Ngaphezu kwalokho, i-hydroxyproline nayo itholakala ku-elastin, ebhekene ne-turgor yesikhumba ejwayelekile. Ngenxa yokuba khona kwale-amino acid emzimbeni wethu, i-collagen iyakwazi ukugcina ukuzinza futhi ingenza ngempumelelo imisebenzi yayo.
Ukudla okunothile kwe-Hydroxyproline:
Izici ezijwayelekile ze-hydroxyproline
Ngaphandle kokuthi i-hydroxyproline iyi-amino acid engabalulekile, ubukhona bayo emzimbeni wethu buhlobene kakhulu nokuba khona kwezinto ezimbili ezibalulekile ekwakheni le nhlanganisela. Izithako ezibalulekile yi-amino acid proline ne-ascorbic acid. Kuphela uma bukhona lapho kungenziwa khona i-hydroxyproline.
Imfuneko yansuku zonke ye-hydroxyproline
Imfuneko yansuku zonke ye-hydroxyproline, ngokusho kocwaningo olwenziwe ososayensi baseDenmark, ayikwazi ukuba ngaphansi kwama-5 amagremu. Kufanele kugcizelelwe ukuthi le amino acid ifakwa ngempumelelo ngumzimba kuphela lapho kukhona i-ascorbic acid.
Ngokuya ngalokhu, singasho ukuthi lapho udla ukudla okunothe ku-proteinogenic amino acid - i-hydroxyproline, kufanele futhi usebenzise uvithamini C. Futhi njengoba uvithamini C okhule emibhedeni nasemagatsheni ezihlahla kusiza kakhulu emzimbeni wethu, kufanele yisebenzise, okungcono kanye nemifino, izithelo, amakhambi.
Isidingo se-hydroxyproline sanda nge:
- i-toxicosis yabesifazane abakhulelwe;
- kwehlisa amasosha omzimba;
- ukudana kanye nezimo ezifanayo;
- ukudakwa okujwayelekile komzimba;
- ukwanda komthwalo wobuchopho;
- izimo ezicindezelayo;
- ukukhathala okwandisiwe komzimba;
- ukuqina kwemisipha;
- ukulahleka kwegazi okuningi (kufaka phakathi nokuya esikhathini);
- amanxeba, ukulimala nezinye izimo lapho ubuqotho bemisipha nesikhumba kungasebenzi khona.
Isidingo se-hydroxyproline sincipha nge:
- ukungabekezelelani ne-hydroxyproline;
- izifo ezihambisana nokukhubazeka okungalungile;
- Isifo sikaPaget.
Ukugaya kwe-hydroxyproline
Ngenxa yokuthi i-hydroxyproline yakhiwa kusuka ku-amino acid proline kuphela lapho kukhona i-ascorbic acid, ukumuncwa kwayo kuhlotshaniswa novithamini C. Ngenxa ye-vitamin C, le amino acid ayitholwa kahle hhayi kuphela emgodini wamathumbu, kodwa futhi ezingeni lezingqamuzana zeseli…
Izakhiwo eziwusizo ze-hydroxyproline nomphumela wayo emzimbeni:
I-Hydroxyproline inesibopho sokuhlangabezana nezidingo ezilandelayo zomzimba wethu:
- kuthuthukisa isimo sesikhumba;
- inikeza ukuhlanganiswa kanye nokulondolozwa kwe-glycogen emisipheni nasesibindi;
- ubamba iqhaza ekususeni imiphumela yokufaka ushevu emzimbeni wethu;
- isheshisa futhi ithuthukise imetabolism;
- yenza kusebenze umsebenzi we-pituitary gland;
- kuvusa ukuhlanganiswa kwamahomoni adrenal ne-thyroid;
- iqhaza ekwakhekeni kwamaprotheni compounds afana ne-elastin ne-collagen;
- isheshisa ukuvuselelwa kwamathambo;
- kusheshisa ukuphulukiswa kwesilonda;
- uthatha ingxenye esebenzayo kwinqubo ye-hematopoiesis;
- kubeka ingcindezi emithanjeni yegazi nemithambo yegazi
- kuthuthukisa ukuzivikela komzimba;
- unomphumela we-analgesic;
- ithuthukisa umsebenzi wepheshana lamathumbu;
- kunciphisa ukungezwani kwangaphambi kokuya esikhathini;
- kunciphisa ikhanda, kanye nobuhlungu obuhambisana nezifo zamalunga nomgogodla.
Ukusebenzisana nezinye izinto:
Ngokuqondene nezinto ezibalulekile, izakhi ezisemqoka lapho i-hydroxyproline ihlangana khona yi-proteinogenic amino acid proline no-vitamin C. Kubonga kubo ukuthi i-hydroxyproline iyakwazi ukwenza umthelela onjalo emisebenzini eyisisekelo yomzimba wethu.
Izimpawu zokuntuleka kwe-hydroxyproline emzimbeni:
- ubuthakathaka bemisipha kanye ne-dystrophy;
- i-anemia (amazinga aphansi we-hemoglobin egazini);
- ukusebenza kobuthakathaka kobuchopho, okuvame ukuphenduka isithukuthezi;
- izinkinga zesikhumba;
- ikhanda elibuhlungu njalo nezinhlungu zokuya esikhathini;
- ukuphazamiseka komzimba;
- izinkinga zomsebenzi wokukhipha (ukukhishwa kwamakhemikhali ayingozi kuphazamisekile).
Izimpawu ze-hydroxyproline eyeqile emzimbeni:
Azikho neze izimpawu zokugcwala ngokweqile kwe-hydroxyproline ocwaningweni lwezokwelapha. Ngokwethiyori, kukholelwa ukuthi singakhuluma ngokweqile kwe-hydroxyproline kuphela uma kune-vitamin C eyeqile emzimbeni ngokuhlangana ne-proline eyeqile. Ezimweni ezingavamile kakhulu, kungahle kube nokungabekezelelani ngakunye kwalolu ketshezi, okubonakaliswa ukusabela okweqile.
Izici ezithinta okuqukethwe kwe-hydroxyproline emzimbeni:
Izindlela ezisemqoka zokutholakala kwe-hydroxyproline emzimbeni yilezi:
- ukutholakala kwezingxenye eziyinhloko ze-synthesis ye-hydroxyproline (i-proline ne-vitamin C);
- ukuhlanganiswa okugcwele kwale amino acid ngumzimba wethu;
- ukungabikho kwezifo lapho i-hydroxyproline iyeka ukumuncwa.
I-Hydroxyproline yobuhle nempilo
Esihlokweni esikhuluma nge-amino acid proline, sesivele sikhulume ngemiphumela yale asidi esikhunjeni nasezicukweni ezixhumanisayo. Ngokuqondene ne-hydroxyproline, ngoba le nto isuselwa ku-proline no-vitamin C, imiphumela yayo nayo ihlobene kakhulu nobuhle. Ngenxa ye-hydroxyproline, isikhumba asigcini nje ngokuthuthukisa i-turgor yaso, kodwa futhi sigcwele umswakama, futhi sithola namandla angeziwe ngenxa yobukhona be-ascorbic acid.