Le iron iyingxenye ebalulekile yeelithwala umoya-mpilo, amaprotheni akhona Amaseli abomvu futhi umsebenzi wawo omkhulu uwukuthuthaOksijini kuinhlangano.

Ibalulekile futhi nakweminye imisebenzi yomzimba, njengokwakheka kwe-DNA noma ukusabela okuthile kwe-enzymatic.

Cishe amaphesenti angama-70 ensimbi yomzimba eboshiweelithwala umoya-mpilo, kuyilapho okunye kugxilile amaprotheni okuthutha (The ferritin or i-transferrin) noma agcinwe ezicutshini ezithile zomzimba. Ngokwesibonelo, emnkantsheni, insimbi igcinwa futhi isetshenziswe njengoba kudingeka ukuze kwakhiwe amangqamuzana egazi abomvu amasha.

Insimbi ivelaukudla (isibindi nezinye inyama, amaqanda, inhlanzi, noma imifino eluhlaza). Kudingeka ikakhulukazi ngesikhathi sokukhula, ukukhulelwa, ukuncelisa ibele noma ngemva kokopha kakhulu.

Ukuhlolwa kukuvumela ukuthi uhlole izinga lensimbi emzimbeni nokuthi linjani i-metabolized (okungukuthi kufakwe umzimba). Lokhu kuvumela udokotela ukuthi ahlonze ngokwesibonelo ukushoda kwe-iron (ukuntuleka kwe-iron), ukuntuleka kwe-iron anemia (i-anemia ngenxa yokuntuleka kwe-iron), i-hemochromatosis (insimbi eyeqile emzimbeni), kodwa futhi nokuhlola isimo somsoco wesiguli.

Isexwayiso: ukuzimisela kwe-ferritin kuvame ukwenziwa kuqala, umthamo we-iron wodwa awuvamile ukuboniswa (ungenziwa ngomthamo we-transferrin ngenhloso yesibili).

Izinga legolide lokulinganisa inani lensimbi emzimbeniukuhlolwa komnkantsha, kusuka ekufuneni umnkantsha noma i-biopsy. Ukuhlola okuhlaselayo nokuhlukumezayo ngakho-ke akwenziwa ngendlela evamile.

Ukunqunywa kwe-iron serum (egazini) kungenziwa ngesampula yegazi le-venous, ngokuvamile ethathwe ekugoqeni kwendololwane. Akuvamile ukuthi kwenziwe iyodwa ngoba inenani elincane lokuxilonga. Ngokuvamile, ihlanganiswa nezinye izivivinyo ezinjengaleyo ye-serum transferrin, futhi ngezinye izikhathi eye-serum ferritin, i-soluble transferrin receptors noma i-intraerythrocytic ferritin.

Njengoba izinga lensimbi liphakeme ekuseni, ukuhlolwa kufanele kwenzeke ngalesi sikhathi sosuku.

Izinga lensimbi egazini livamise ukuba phakathi kuka-70 no-175 μg/dl (ama-micrograms nge-deciliter) emadodeni naphakathi kuka-50 no-150 μg/dl kwabesifazane, kodwa liyahlukahluka kakhulu kumuntu ofanayo phakathi nosuku (amplitude yama-30 kuye kwangama-40). %). Yingakho kubalulekile ukuhlobanisa umthamo we- i-transferrin kanye nokubala i-transferrin saturation coefficient.

Amazinga aphezulu e-iron serum angase abe uphawu, phakathi kwezinye izinto:

• a i-hemochromatosis  (i-ayoni egcwele kakhulu)
• i-hemolytic anemia (ukubhujiswa ngaphambi kwesikhathi kwamaseli abomvu egazi)
• i-hepatic necrosis
• i-hepatitis (ukuvuvukala kwesibindi)
• i-cirrhosis
• ukuphuza ngokweqile
• ukumpontshelwa igazi ngokuphindaphindiwe

Ngokuphambene nalokho, izinga eliphansi lensimbi lingaxhunyaniswa nalokhu:

• ukulahlekelwa okukhulu kwegazi, ikakhulukazi ngezikhathi ezinzima
• ukukhulelwa
• ukuntuleka kwe-iron (ukuntuleka kwe-iron) okuhlobene nokudla
• ukuntula okuhlobene nokungakwazi ukumunca kahle insimbi
• ukopha emgudwini wamathumbu (izilonda, umdlavuza wekoloni, ama-hemorrhoids)

kodwa futhi ukuvuvukala, ukutheleleka, ngemva kokuhlinzwa, njll.

Nakulokhu futhi, kufanele kuqashelwe ukuthi lesi silinganiso, okwenziwa ngasodwa, asinaso isithakazelo sezokwelapha.