Okuqukethwe
- Reversible acetylcholinesterase inhibitors ekwelapheni i-Alzheimer's
- I-N-methyl-D-aspartate agonists ekwelapheni i-Alzheimer's
- I-Neuroleptics ekwelapheni i-Alzheimer's
- Izidakamizwa zokuthuthukisa ukugeleza kwegazi emithanjeni ye-cerebral ekwelapheni i-Alzheimer's
- Ama-antidepressants ekwelapheni i-Alzheimer's
- I-Hypnotics ekwelapheni i-Alzheimer's
- Imithi etholakala ngaphandle kwekhawunta ye-Alzheimer's
Ngokuvumelana nomsebenzi walo, Ibhodi Lokuhlela le-MedTvoiLokony lenza yonke imizamo yokuhlinzeka ngokuqukethwe kwezokwelapha okuthembekile okusekelwa ulwazi lwakamuva lwesayensi. Ifulegi elengeziwe elithi "Okuqukethwe Okuhloliwe" libonisa ukuthi i-athikili ibuyekezwe noma yabhalwa udokotela ngokuqondile. Lokhu kuqinisekisa okuyizinyathelo ezimbili: intatheli yezokwelapha kanye nodokotela basivumela ukuthi sinikeze okuqukethwe kwekhwalithi ephezulu ngokuhambisana nolwazi lwamanje lwezokwelapha.
Ukuzibophezela kwethu kule ndawo kuye kwathakaselwa, phakathi kokunye, yiNhlangano Yezintatheli Zezempilo, eyaklomelisa Ibhodi Lokuhlela le-MedTvoiLokony ngesihloko sokuhlonipha esithi Umfundisi Omkhulu.
Iningi labantu asebekhulile lihlushwa isifo i-Alzheimer's. I-Dementia ayikwazi ukwelapheka ngokuphelele, kodwa imithi ekhethwe kahle izobambezela ukuqhubeka kwayo. Bazophinde banciphise izimpawu eziyinkinga. Sethula izidakamizwa ezivame ukukhethwa ngochwepheshe, ezilungiselelwa iminyaka yesiguli kanye nokuqhubeka kwesifo.
Reversible acetylcholinesterase inhibitors ekwelapheni i-Alzheimer's
Ama-reversible acetylcholinesterase (AChE) inhibitors athathwa ekuqaleni kwesifo. Okuvame ukusetshenziswa kakhulu yi-donepezil, i-rivastigmine ne-galantamine (ayibuyiselwa imali). I-Tacrine isetshenziswa kancane ngenxa yemiphumela yayo emibi. Eminye imithi yabantu abangaphezu kweminyaka engama-75 iyabuyiselwa. Ama-AChE athuthukisa inkumbulo futhi anciphise izimpawu zesifo. Nokho, angabangela imiphumela engemihle efana nokuqunjelwa kwemisipha, ukuqwasha kanye nesifo sohudo.
I-N-methyl-D-aspartate agonists ekwelapheni i-Alzheimer's
Ama-agonists e-N-methyl-D-aspartate (NMDA) avikela amangqamuzana ezinzwa ekuwohlokeni okuphelele. Ama-Agonists afaka phakathi, i-memantine okufanele inikezwe kanye ne-donepezil. I-NMDA isetshenziswa ezigulini ezinenkinga ye-Alzheimer's emaphakathi kuya kokuqina.
I-Neuroleptics ekwelapheni i-Alzheimer's
I-Neuroleptics yizidakamizwa ze-psychotic okufanele zinciphise izimpawu ze-schizophrenia kanye ne-psychosis. Bangase bahlotshaniswe nesifo i-Alzheimer's. Imvamisa, iziguli zithola i-clozapine noma i-risperidone.
Izidakamizwa zokuthuthukisa ukugeleza kwegazi emithanjeni ye-cerebral ekwelapheni i-Alzheimer's
Ekwelapheni i-Alzheimer's, izidakamizwa ezithuthukisa ukugeleza kwegazi emithanjeni yobuchopho ziye zabonakala zifiseleka kakhulu. Bathuthukisa izinqubo zengqondo zesiguli. Okuvame ukushiwo udokotela yi-choline precursor, i-ginkgo biloba extract, i-selegiline ne-vinpocetine.
Ama-antidepressants ekwelapheni i-Alzheimer's
Enye yezimpawu ezikhathazayo ze-Alzheimer's ukushintsha kwemizwa okuvame ukuholela ekucindezelekeni. Kulokhu, iziguli zinikezwa ama-serotonin reuptake inhibitors akhethiwe. Zingathathwa ngaphambi kokulala njengoba zinomphumela wokuzola. Ngaphandle kwemithi, isiguli kufanele futhi sidluliselwe ku-psychotherapy.
I-Hypnotics ekwelapheni i-Alzheimer's
Abantu abalwa nesifo i-Alzheimer's nabo banganikezwa amaphilisi okulala asebenza isikhathi esifushane. Uma isiguli sikhathazekile, kufanele sithathe imithamo enamandla. Izidakamizwa eziqukethe i-axazepam kanye ne-benzodiazepines ziyafiseleka. Kodwa-ke, phakathi kwemiphumela emibi engathandeki, ukuvuselela ngokweqile kuyashiwo.
Imithi etholakala ngaphandle kwekhawunta ye-Alzheimer's
Imithi ethengwayo ingase futhi ibe nezinto eziwusizo ekwelapheni isifo i-Alzheimer's. Lokhu kufaka phakathi amaphilisi e-colostrinin ukuvimbela ukwakheka kwe-age plaque (beta-amyloid). I-Coenzyme Q10 kanye namavithamini A no-E nawo abambezela inqubo yokuguga. Okufanayo kuyiqiniso nangemithi engeyona i-steroidal eqeda ukuvuvukala, engathathwa isikhathi eside.