Phakathi kweminyaka engu-20 nengu-79, cishe owesifazane oyedwa kwabayishumi ubika ukuthi uphuza utshwala nsuku zonke futhi cishe abane kwabayishumi isonto ngalinye. Kunokwehluka kwezenhlalo nabasebenzisi besilisa abedlulele: kuyilapho abokugcina bebaningi kakhulu emakilasini abahlelelekile kwezenhlalo nezobuchwepheshe futhi bangahlasela utshwala ekuseni endaweni yokucima ukoma, abesifazane abathintekayo bathola izikhundla zokuzibophezela. futhi uphuze wedwa, ukucwilisa ingcindezi yabo. Omunye umehluko ophawulekayo: uma umshado uyinto evikela kakhulu amadoda, akuwona owabesifazane. 

Ngokwezokwelapha, izingozi - i-hepatic cirrhosis, umfutho wegazi ophakeme, i-cardiomyopathy kanye nokopha kwamathumbu - ziyanda kwabesifazane, ingasaphathwa izingozi zokuphuphuma kwesisu kanye nesifo sotshwala bengane ekukhulelweni. Ngenhlanhla, abesifazane abayizigqila zophuzo oludakayo babonakala bekhuthalele ukuzikhulula (ikakhulukazi ukuthi bangabe besacwaswa futhi bangalahlekelwa izingane zabo) nalapho ukunakekelwa kwabo kokwelapha kulungiswa, nokulawulwa kokunye ukulutheka, ukuphazamiseka. ukuziphatha kokudla, ukukhathazeka, ukudangala, njll., amathuba abo okuphumelela mahle.