Kusukela isencane kakhulu, ingane ene-Down's syndrome inezici zomzimba ezibonakalayo:

• Iphrofayili "ebendile".
• Amehlo atshekile.
• I-epicanthus (= amafolda esikhumba ngenhla kwejwabu leso eliphezulu).
• Ibhuloho elisicaba lamakhala.
• I-Hypertrophy nokuqhamuka kolimi (ulimi luqhubekele phambili ngokungajwayelekile).
• Ikhanda elincane nezindlebe ezincane.
• Intamo emfushane.
• Isigaxa esisodwa ezintendeni zezandla, esibizwa nge-crease palmar crease eyodwa.
• Ubuncane bezitho kanye nesiqu.
• I-muscle hypotonia (= yonke imisipha ithambile) namalunga aguquguqukayo ngokungajwayelekile (= i-hyperlaxity).
• Ukukhula kancane futhi ngokuvamile kuncane ukuphakama kunezingane ezineminyaka efanayo.
• Ezinganeni, ukubambezeleka kokufunda njengokujika, ukuhlala nokukhasa ngenxa yokungahambi kahle kwemisipha. Lokhu kufunda ngokuvamile kwenziwa ngeminyaka ephindwe kabili yezingane ezingenayo i-Down's syndrome.
• Ukubambezeleka okulingene kuya kokulingene.

Izinkinga

Izingane ezine-Down's syndrome ngezinye izikhathi ziba nezinkinga ezithile:

• Ukukhubazeka kwenhliziyo. Ngokwe-Canadian Down Syndrome Society (SCSD), ngaphezu kwama-40% wezingane ezine-syndrome zinenkinga yokuzalwa ekhona kusukela zizalwa.
• A ukunyuka (noma ukuvimbela) uma kwenzeka kuba edinga ukuhlinzwa. Ithinta cishe u-10% wezinsana ezisanda kuzalwa ezine-Down's syndrome.
• A ukulahlekelwa kukuzwa.
• A ukutholakala kokutheleleka njengesibonelo inyumoniya, ngenxa yokwehla kokuzivikela komzimba.
• Ingozi eyengeziwe ye-hypothyroidism (i-hormone ephansi ye-thyroid), i-leukemia noma ukuhlaselwa.
• Un ukubambezeleka kolimi, kwesinye isikhathi kubhebhethekiswa ukungezwa.
• izinzuzo izinkinga zamehlo nokubona (i-cataract, i-strabismus, i-myopia noma i-hyperopia ivame kakhulu).
• Ingozi eyengeziwe yokuphefumula kokulala.
• Ukuthambekela kokukhuluphala.
• Emadodeni athintekile, inzalo. Ukukhulelwa noma kunjalo kungenzeka kwabesifazane abaningi.
• Abantu abadala abanalesi sifo nabo bathambekele kakhulu ekubeni nesifo i-Alzheimer's esiqala ukusheshe sivele.