I-Pepsinogen iyi-enzyme yokugaya ekhiqizwa izindonga zesisu sabantu nezinye izinhlobo eziningi zezilwane. Ngaphansi kwethonya lendawo ene-asidi yesisu (i-pH ezungeze i-2) noma i-pepsin ngokwayo (okuthiwa i-autoactivation), ishintsha ibe yi-pepsin, umsebenzi wayo oyinhloko ukugaya amaprotheni kusengaphambili. Ngesikhathi sokugaya, i-pepsin idiliza amaprotheni abe amaketanga amafushane e-polypeptides nama-oligopeptides, okuthi ngokuhamba kwesikhathi ezinqubweni zokugaya ezenzeka emathunjini amancane ahlukaniswe abe ama-amino acid ngamanye. Ngaphansi kwethonya lezinto ezengeziwe, ezifana nokuba khona kokudla esiswini noma i-acidification ye-mucosa, ukugcinwa kwayo kuyanda.
I-Pepsin - ukusetshenziswa kwezokwelapha
Isidakamizwa sitholakala ku-mucosa esiswini sezingulube, amathole noma izimvu. Ukugaya amaprotheni kuqala ku-pH engaphansi kuka-4; ukugxila okuphezulu kakhulu kwe-hydrochloric acid akusebenzi Pepsi. Amalungiselelo i-pepsyny zandisa isifiso sokudla, zenza i-pH yejusi yesisu ibe ngokwejwayelekile, futhi zenze kube lula ukugayeka kokudla amaprotheni esiswini.
I-Pepsin - izinkomba
Amalungiselelo aqukethe Pepsi sebenzisa:
- ezifweni ezinokukhiqizwa okunganele kwe-pepsin ye-endo native,
- ngokungabi naso isifiso sokudla,
- ku-asidi,
- ekwehliseni ukukhishwa kwesisu,
- ku-gastritis engapheli,
- izinqubo zokuvutshelwa okukhulu kakhulu,
- ku-gastritis eyingozi futhi engapheli,
- izimo ngemuva kwe-gastrectomy,
- ukuphazamiseka kokugaya ukudla okubangelwa isifo sesibindi.
Izimpawu ze-acidosis kanye ne-acidity kungase kufane komunye nomunye, ngakho-ke ukuxilonga kubalulekile. Iziguli zivame ukukhononda ngezimpawu ezingemnandi ngokushesha ngemva kokudla. Lezi yizi: umuzwa wokuchichima, ubuhlungu esiswini kanye nendawo ezungezile, umuzwa wobunzima endaweni yesisu. Kungase kube negesi, isilungulela, isizungu, isicanucanu, noma izinkinga zokuhamba kwesisu njengokuhuda noma ukuqunjelwa. Kwesinye isikhathi isifo sohudo nokuqunjelwa kuyashintshana. Uhudo oluhlala isikhathi eside luyawohloza umzimba futhi lwenza isiguli sibe buthaka. Ukugula ayikugayisi kahle ukudla, ayimundi ama-micro- and macroelements adingekayo. Lapho isisu sikhiqiza ijusi elincane kakhulu lokugaya ukudla, ukudla akugayeki kahle. Izithako okunzima ukuzigaya noma ukuphakelwa ngendlela engafanele (okungaphekwa kahle, okungahlafunwanga ngokuphelele) zizocutshungulwa ngokwengxenye kuphela, okudingekayo ukuze zisetshenziswe ngokugcwele futhi zixutshwe. Nasi isizathu ukuswelekaI-ayoni inzima kakhulu ukukunikeza uma une-asidi, njengoba itholakala kakhulu enyameni, okunzima ukuyigaya. Kukhona ne-malabsorption ye-magnesium, i-zinc (ngakho, phakathi kokunye, izinkinga zesikhumba, izinzipho nezinwele) kanye ne-calcium. Ucwaningo lubonisa ukuthi inani elifanele le-hydrochloric acid liyadingeka ukuze kufakwe kahle amavithamini B, ikakhulukazi uvithamini B12. Ukushoda kwale vithamini kuhlotshaniswa ne-anemia, ubuthakathaka obujwayelekile noma ukuphazamiseka kwesimiso sezinzwa, isibonelo ukucindezeleka. Singase futhi sibe nokungazweli kahle ekuthelelekeni, ngoba ukumuncwa kukavithamini C kubi kakhulu kubantu abane-asidi ephansi esiswini. Uma kunezimpawu ezifanayo, bonana nodokotela. Ukufana kwezimpawu ze-gastric hyperacidity kanye ne-acidity kudinga ukuxilonga okufanele, futhi ngokufinyelela kuma-antacid adumile, singazilimaza ngokwethu.
Pepsin - umthamo
Umthamo unqunywa ngamunye kuye ngokuthi ulungiselelwe, izinkomba zokusetshenziswa kwawo kanye nesimo sesiguli. Amalungiselelo i-pepsyny ilawulwa ngokushesha ngaphambi noma ngesikhathi sokudla.
Amalungiselelo emakethe yasePoland equkethe Pepsiezitholakala emakhemisi yilezi:
- I-Citropepsin (uketshezi),
- I-Bepepsin (amaphilisi),
- I-Mixtura Pepsini, ingxube ye-pepsin (uketshezi) - itholakala ngokunikezwa ngudokotela ekhemisi.
Pepsina kubuye kube yingxenye evamile yezithako zokudla ukuze kube lula ukugaya noma ukulwa nokukhuluphala ngokweqile.