La isilinganiso sedimentation isivivinyo esikala i isilinganiso sedimentation, noma ukuwa kwamahhala kwamangqamuzana abomvu egazi (amangqamuzana abomvu egazi) kusampula yegazi elishiywe eshubhuni eliqondile ngemva kwehora elilodwa.

Lesi sivinini sincike ekugxilweni kwe amaprotheni egazini. Iyahluka ikakhulukazi uma kwenzekaukuvuvukala, lapho amazinga amaprotheni avuvukalayo, i-fibrinogen noma ngisho nama-immunoglobulins anda. Ngakho-ke ngokuvamile isetshenziswa njengophawu lokuvuvukala.

Lokhu kuhlolwa kuvame uku-oda ngesikhathi esifanayo ne-i-hemogram (noma inani legazi). Iya ngokuya ithathelwa indawo ukuhlolwa okufana nokukalwa kwe-CRP noma i-procalcitonin, okuvumela ukuvuvukala kuhlolwe ngokunembe kakhudlwana.

Izinga le-sedimentation lingabalwa ezimeni ezimbalwa, ikakhulukazi:

• bheka ukuvuvukala
• hlola izinga lomsebenzi wezifo ezithile ze-rheumatic ezivuthayo njenge-arthritis ye-rheumatoid
• thola ukungavamile kwama-immunoglobulins (hypergammaglobulinemia, monoclonal gammopathy)
• qaphela ukuqhubeka noma thola i-myeloma
• esimweni se-nephrotic syndrome noma ukwehluleka kwezinso okungapheli

Lokhu kuhlola kuyashesha, akubizi kodwa akucaci kahle futhi akusafanele kuboniswe ngendlela ehlelekile ekuhlolweni kwegazi, ngokwezincomo zeSiphathimandla Esiphezulu Sezempilo eFrance.

Ukuhlolwa kusekelwe kusampula yegazi elilula, okungcono kakhulu ukuthi kwenziwe esiswini esingenalutho. Izinga le-sedimentation kufanele lifundwe ihora elilodwa ngemuva kokuqoqwa.

Umphumela uvezwa ngamamilimitha ngemva kwehora elilodwa. Izinga le-sedimentation liyahlukahluka ngokobulili (ngokushesha kwabesifazane kunabesilisa) kanye neminyaka (ngokushesha kubantu abadala kunasebasha). Kuyanda futhi ngesikhathi sokukhulelwa nalapho uthatha imithi ethile ye-estrogen-progestogen.

Ngemva kwehora, ngokuvamile, umphumela kufanele ube ngaphansi kuka-15 noma 20 mm ezigulini ezincane. Ngemuva kweminyaka engama-65, imvamisa iba ngaphansi kuka-30 noma 35 mm kuye ngobulili.

Futhi singaba nesilinganiso samanani avamile, okufanele ahlale ephansi kunalokhu:

- kwabesilisa: VS = iminyaka ngeminyaka / 2

- kwabesifazane: VS = iminyaka (+10) / 2

Lapho izinga le-sedimentation lenyuka kakhulu (cishe i-100 mm ngehora), umuntu angase ahlupheke:

• ukutheleleka,
• isimila esiyingozi noma i-myeloma eminingi,
• isifo sezinso esingamahlalakhona,
• isifo sokuvuvukala.

Ezinye izimo ezingavuvukali ezifana ne-anemia noma i-hypergammaglobulinemia (isibonelo esibangelwa i-HIV noma i-hepatitis C) nazo zingandisa i-ESR.

Ngokuphambene nalokho, ukwehla kwezinga le-sedimentation kungabonakala esimweni salokhu:

• i-hemolysis (ukubhujiswa okungavamile kwamangqamuzana abomvu egazi)
• i-hypofibrinemia (ukwehla kwamazinga e-fibrinogen),
• i-hypogammaglobulinémie,
• i-polycythemia (evimbela i-sedimentation)
• ukuthatha izidakamizwa ezithile zokulwa nokuvuvukala ngemithamo ephezulu
• njll

Ezimweni lapho izinga le-sedimentation liphakeme ngokusesilinganisweni, isibonelo phakathi kuka-20 no-40 mm / h, ukuhlolwa akucacile kakhulu, kunzima ukuqinisekisa ukuba khona kokuvuvukala. Okunye ukuhlolwa okufana nokuhlolwa kwe-CRP nokuhlolwa kwe-fibrinogen cishe kuyodingeka.