I-Lipanthyl Supra - ukwakheka, isenzo, izinkomba, imiphumela emibi. Ungayithatha kanjani i-Lipanthyl Supra?

Okuqukethwe okuqinisekisiwe

I-Lipanthyl Supra umuthi owehlisa i-lipid egazini. Isithako esisebenzayo kuLipanthyl Supra yi-fenofibrate. Funda indlela yokuthatha i-Lipanthyl Supra nokuthi imiphi imiphumela emibi engayibangela.

I-Lipanthyl Supra - ihambisana ne-lek?

I-Lipanthyl Supra (160 mg / 215 mg) iyisidakamizwa esikhonjiswe ukusetshenziswa njengesengezo ekudleni nezinye izindlela zokwelapha ezingezona ezemithi (isib. Ukuzivocavoca umzimba, ukwehla kwesisindo) kulezi zimo ezilandelayo:

1. ukwelashwa kwe-hypertriglyceridaemia enzima ene-cholesterol ye-HDL noma ngaphandle kwayo
2. i-hyperlipidemia ehlanganisiwe lapho ukusetshenziswa kwe-statin kuvinjelwe noma kungabekezelelwa,
3. i-hyperlipidemia exubile kubantu abasengozini enkulu yokuba nesifo senhliziyo nemithambo yegazi, ngaphezu kokwelashwa nge-statin, lapho i-triglycerides ne-high-density cholesterol (HDL) ingalawulwa ngokwanele.

Isithako esisebenzayo sokulungiselela I-Lipanthyl Supra i-fenofibrate. Kungokweqembu lemithi ebizwa ngokuthi ama-fibrate asetshenziselwa ukwehlisa amazinga e-lipids (cholesterol, triglycerides) egazini.

Funda:Yenyusa i-cholesterol futhi ibulale umzimba. Lobu tshwala bubi kakhulu

I-Lipanthyl Supra - indlela yokusebenza

I-Fenofibrate, into esebenzayo. I-Lipanthyl Supra iphuma ku-fibric acid, umphumela wokuguqula i-lipid kubantu ufinyelelwa ngokusebenza kwama-nuclear receptors ohlobo lwe-α (PPARα, Peroxisome Proliferator Activated Receptor type α).

Ngokucupha i-PPARα, i-fenofibrate inyusa i-lipolysis kanye nokuqedwa kwezinhlayiya ze-atherogenic ezicebile ku-serum triglyceride ngokwenza kusebenze i-lipoprotein lipase nokunciphisa ukukhiqizwa kwe-apolipoprotein CIII.

Ukwenza kusebenze i-PPARα futhi kuholela ekwandeni kokuhlanganiswa kwama-apolipoprotein AI ne-AII. Umphumela we-fenofibrate kuma-lipoprotein uholela ekwehleni kwezingxenyana eziphansi kakhulu neziphansi (VLDL ne-LDL) eziqukethe i-apolipoprotein B kanye nokwanda kwengxenyana ye-high density lipoprotein (HDL) equkethe ama-apolipoprotein AI ne-AII.

I-Fenofibrate ikhishwa ikakhulukazi emchamweni. Iqedwa ngokuphelele phakathi nezinsuku eziyisi-6. I-Fenofibrate ikhishwa ikakhulukazi ngesimo se-fenofibric acid kanye nokuphuma kwayo kwe-glucuronide.

Bheka: I-cholesterol ephelele, i-LDL ne-HDL. Ungayehlisa kanjani i-cholesterol?

I-Lipanthyl Supra - umthamo

Njalo thatha i-Lipanthyl Supra njengoba nje udokotela wakho noma usokhemisi ekutshele. Hlola nodokotela wakho noma usokhemisi uma ungaqiniseki. Udokotela wakho uzonquma umthamo olungile womuthi kuye ngesimo sakho sezempilo.

Ithebhulethi yeLipanthyl Supra kufanele igwinywe ngengilazi yamanzi. Ukulungiswa kufanele kuthathwe ngokudla, njengoba ukumuncwa kwesidakamizwa esiswini esingenalutho kubi kakhulu.

Umthamo we-Lipanthyl Supra umi kanje.

Abantu abadala

1. umthamo onconyiwe yithebhulethi eyi-1 160 mg / 215 mg enefilimu nsuku zonke.
2. abantu okwamanje abathatha amaphilisi aqukethe 200 mg fenofibrate (1 capsule ngosuku) bangaqala ukuthatha ithebhulethi 1 160 mg ngosuku ngaphandle kokulungiswa umthamo.

Abantu abanokwehluleka kwezinso

Kubantu abanokwehluleka kwezinso, udokotela angase anciphise umthamo. Uma kwenzeka ukuphazamiseka okunjalo, thintana nodokotela wakho noma usokhemisi. Kubantu abanokwehluleka okukhulu kwezinso (imvume ye-creatinine ngaphansi kwe-20 ml / min), umuthi uyaphikiswa.

Abantu asebekhulile

Ezigulini esezikhulile ezingenakho ukungasebenzi kahle kwezinso, umthamo onconywayo wabantu abadala ngu.

Abantu abanenkinga yesibindi

I-Lipanthyl Supra ayinconywa ngenxa yokuntuleka kwedatha yomtholampilo kubantu abanokungapheleli kwesibindi.

Sebenzisa ezinganeni nasebusheni

Ukusetshenziswa kweLipantil Supra ezinganeni nasentsheni engaphansi kweminyaka engu-18 akunconywa.

Ibhodi labahleli lincoma: Ukwehluleka kwezitho eziningi - i-Multiorgan dysfunction syndrome (MODS)

I-Lipanthyl Supra - i-contraindication

I-contraindication eyinhloko ekusetshenzisweni kwe-Lipanthyl Supra yi-hypersensitivity entweni esebenzayo yomuthi noma izinto ezisizayo. Ngaphezu kwalokho, i-Lipanthyl Supra ayinconyelwe:

1. ukwehluleka kwesibindi (kubandakanya i-biliary cirrhosis kanye nokungasebenzi kahle kwesibindi isikhathi eside),
2. isifo se-gallbladder,
3. ukwehluleka okukhulu kwezinso (eGRF <30 ml / min / 1,73 m2),
4. i-pancreatitis engapheli noma ebukhali ngaphandle kwe-pancreatitis eyingozi ngenxa ye-hypertriglyceridemia enzima,
5. i-photosensitivity noma ukusabela kwe-phototoxic lapho usebenzisa ama-fibrate noma i-ketoprofen.

Abesifazane abakhulelwe nabancelisayo kufanele babonane nodokotela ngaphambi kokusebenzisa i-Lipanthyl Supra. Ngokuvamile, akufanele uthathe lokhu kulungiselelwa ngesikhathi sokukhulelwa nokuncelisa.

I-Lipanthyl Supra akufanele isetshenziswe kubantu abazwela kakhulu amantongomane, uwoyela wamantongomane, i-soy lecithin noma okuphuma kuyo ngenxa yengozi yokusabela kwe-hypersensitivity.

Ibhodi labahleli lincoma: Ukwanda kwe-lipase ne-pancreatitis

I-Lipanthyl Supra - izinyathelo zokuphepha

Khuluma nodokotela wakho noma usokhemisi ngaphambi kokuthatha i-Lipanthyl Supra 160 uma:

1. babe nezinkinga zesibindi noma izinso
2. abe nokuvuvukala kwesibindi, izimpawu zihlanganisa ukuba phuzi kwesikhumba nokubamhlophe kwamehlo (i-jaundice) kanye namazinga anda ama-enzyme esibindi (aboniswe ekuhlolweni kwaselabhorethri)
3. unendlala yegilo engasebenzi kahle (ukuncipha kokusebenza kwendlala yegilo).

Uma noma yisiphi sezixwayiso ezingenhla sisebenza kuwe (noma uma ungabaza), thintana nodokotela wakho noma usokhemisi ngaphambi kokuthatha i-Lipanthyl Supra.

I-Lipanthyl Supra - umphumela emisipha

Ngenkathi uthatha i-Lipanthyl Supra ungase uzwe amajaqamba noma ubuhlungu bemisipha obungalindelekile, ukuthamba kwemisipha noma ubuthakathaka ngenkathi uthatha lo muthi. I-Lipanthyl Supra ingabangela izinkinga zemisipha ezingaba nzima. Lezi zimo azivamile kodwa zihlanganisa ukuvuvukala kwemisipha nokuwohloka. Lokhu kungabangela ukulimala kwezinso noma ngisho nokufa.

Udokotela wakho angase ahlole igazi ukuze ahlole isimo semisipha yakho ngaphambi nangemva kokuqala ukwelashwa. Ingozi yokuwohloka kwemisipha ingase ibe nkulu kwezinye iziguli. Sicela wazise udokotela wakho uma:

1. isiguli singaphezu kweminyaka engama-70,
2. abe nesifo sezinso
3. nesifo se-thyroid
4. wena noma othile emndenini wakho unesifo sofuzo semisipha
5. umuntu ogulayo uphuza utshwala obuningi,
6. uthatha imithi yokwehlisa i-cholesterol yakho ebizwa ngokuthi ama-statins, njenge-simvastatin, i-atorvastatin, i-pravastatin, i-rosuvastatin noma i-fluvastatin.
7. umlando wezinkinga zemisipha ngenkathi uthatha ama-statins noma ama-fibrate afana ne-fenofibrate, i-bezafibrate noma i-gemfibrozil.

Uma elinye lamaphuzu angenhla livela kumuntu ofuna ukusebenzisa i-Lipanthyl Supra, thintana nodokotela ngaphambi kokuthatha umuthi.

Futhi funda: Statins - isenzo, izinkomba, contraindications, side effects

I-Lipanthyl Supra - ukusebenzisana nezinye izidakamizwa

Ngaphambi kokuthatha i-Lipanthyl Supra, tshela udokotela wakho noma usokhemisi uma uthatha imithi efana nale:

1. ama-anticoagulants athathwa ukuze anciphise igazi (isb i-warfarin)
2. eminye imithi esetshenziselwa ukulawula amazinga amafutha egazi (njengama-statins noma ama-fibrate). Ukuthatha i-statin ngesikhathi esifanayo ne-Lipanthyl Supra kungandisa ingozi yokulimala kwemisipha.
3. Izidakamizwa ezivela eqenjini lemithi esetshenziselwa ukwelapha isifo sikashukela (njenge-rosiglitazone noma i-pioglitazone) - i-cyclosporine (umuthi we-immunosuppressive). 

I-Lipanthyl Supra - imiphumela emibi engenzeka

Imiphumela emibi evame ukubikwa nge-fenofibrate wukuphazamiseka kokugaya ukudla, kwesisu noma kwamathumbu.

Imiphumela emibi ejwayelekile (ingathinta kufika kubantu abayi-1 kwabangu-10):

1. isifo sohudo,
2. ubuhlungu besisu,
3. ukushaywa umoya,
4. isicashunwe,
5. ukuhlanza,
6. ukwanda kwamazinga e-enzyme yesibindi egazini
7. ukwanda kwamazinga e-homocysteine ​​​​egazini.

Imiphumela emibi engajwayelekile (ingathinta kufika kubantu abangu-1 kwabangu-10):

1. ikhanda,
2. i-cholelithiasis,
3. ukwehla kwesifiso socansi,
4. ukuqubuka, ukulunywa noma isifuba
5. ukwanda kwe-creatinine ekhishwa yizinso.