I-Hypertriglyceridemia ibonakala nge amazinga aphezulu kakhulu e-triglyceride egazini. Yize zibalulekile ekusebenzeni kahle komzimba, ama-triglycerides angama-lipids anokweqisa okungaba nemiphumela emibi empilweni.

I-Hypertriglyceridemia ifana ne- a ama-triglycerides amaningi ngaphakathi kwenhlangano. Ama-Triglycerides ngama-lipids avumela ukugcinwa kwamafutha acid ezicutshini ze-adipose. Ngokuya ngezidingo zomzimba, i-triglycerides ingafakwa i-hydrolyzed ukuvumela ukukhishwa kwamafutha acid asetshenziswa njengomthombo wamandla yizitho eziningi. Kodwa-ke, yize zidingekile emzimbeni, lezi lipids zingatholakala ngokweqile futhi zidale izinkinga.

Kubantu abadala, sikhuluma nge-hypertriglyceridemia lapho ukuhlolwa kwe-lipid kuveza i- amazinga we-triglyceride egazi amakhulu kune-1,5 g / L, okungukuthi 1,7 mmol / L. Leli nani lesethenjwa lingahluka ngokwamasu wokuhlaziya ama-triglycerides nemingcele ehlukahlukene enjengobulili nobudala.

Ngokuya ngobukhulu be-triglycerides eyeqile, ingachazwa ngokuthi:

• i-hypertriglyceridemia encane lapho i-triglyceridemia ingaphansi kuka-2 g / L;
• i-hypertriglyceridemia elinganiselayo lapho i-triglyceridemia iphakathi kuka-2 no-5 g / L;
• i-hypertriglyceridemia enkulu lapho i-triglyceridemia ingaphezu kuka-5 g / L.

Kungenzeka ukuhlukanisa ezinye izinhlobo ezimbili ze-triglycerides eyeqile:

• i-hypertriglyceridemia eyedwa, noma okumsulwa, lapho ibhalansi ye-lipid ingadaluli noma iyiphi enye i-dyslipidemia, i-qualitative noma i-anomaly yokulinganisa ye-lipids eyodwa noma ngaphezulu;
• i-hypertriglyceridemia exubile lapho okweqile kwe-triglycerides kuhlotshaniswa namanye ama-dyslipidemias afana ne-hypercholesterolemia, i-cholesterol eyeqile egazini.

Ama-Hypertriglyceridemias nawo angahlukaniswa ngokwezimbangela zawo. Zingabekwa njenge:

• amafomu aphansi, noma ezakudala, lapho zibangelwa ukungajwayelekile kofuzo;
• amafomu wesibili lapho bengenalo imvelaphi yofuzo.

I-triglyceridemia ephezulu ingaba nezimbangela eziningi njenge:

• ukukhubazeka kwezakhi zofuzo ;
• imikhuba emibi yokudla ngokwesibonelo ukusetshenziswa ngokweqile kwamafutha, ushukela notshwala;
• ukuphazamiseka komzimba kufaka phakathi isifo sikashukela, ukukhuluphala ngokweqile nokukhuluphala ngokweqile;
• ukuthatha imithi ethile njengama-corticosteroids, ama-antipsychotic noma ama-antiretrovirals.

Ama-triglycerides amaningi egazini angalinganiswa kunoma yimuphi unyaka. I-Hypertriglyceridemia ingatholakala kubantu abadala kanye nasezinganeni.

I-hypertriglyceridemia ejwayelekile kakhulu yizinhlobo zesibili ezingezona ezemvelo zofuzo. Izimo zofuzo ku-dyslipidemia ziyivelakancane.

Njenganoma imuphi umsoco, i-triglycerides ingaba yingozi uma ikhona ngokweqile emzimbeni. Ubukhulu bemiphumela nokho buxhomeke kumsuka nakwinkambo ye-hypertriglyceridemia.

Uma kuhlotshaniswa ne-hypercholesterolemia, i-hypertriglyceridemia ihlotshaniswa ne- ingozi eyengeziwe yesifo senhliziyo. Uma izinga le-triglyceride likhulu kune-5 g / L, i-hypertriglyceridemia kuthiwa inkulu futhi imele ubungozi obukhulu be i-pancreatitis enamandla (ukuvuvukala kwamanyikwe). Uma kungekho ukwelashwa okwanele, izinga le-triglyceride lingaqhubeka likhuphuke futhi lifinyelele ku-10 g / L. Lo mngcele obucayi wenza isimo esiphuthumayo sezokwelapha.

I-Hypertriglyceridemia ivame ukuba ne-asymptomatic. Kunzima ukukuqonda. Ukuxilongwa kwayo kudinga ukuhlolwa kwegazi.

Kodwa-ke, ezimweni ezibucayi kakhulu, i-hypertriglyceridemia ingazibonakalisa ngezimpawu eziningana ezibandakanya:

• ubuhlungu besisu;
• ukuwohloka kwesimo esijwayelekile;
• ukuqubuka xanthomatosis, ebonakala ngokuvela kwezilonda zesikhumba eziphuzi.

Kunezici eziningana zobungozi ezikhonjwe ngabaphenyi. Phakathi kwalezi zinto, sithola isibonelo:

• ukukhuluphala ngokweqile;
• imikhuba emibi yokudla;
• ukuphuza ngokweqile;
• ukubhema;
• ukungasebenzi komzimba;
• ezinye izifo;
• ukuthatha imithi ethile;
• ukuguga komzimba.

Kungenzeka ukuvimbela ukwanda kwe-triglyceridemia ngokunciphisa izici ezithile zobungozi. Ngenxa yalokhu, kungakuhle ukwamukela izindlela eziningana zokuzivikela:

• ukwamukela ukudla okunempilo futhi olinganiselayo;
• yenza umsebenzi ojwayelekile womzimba;
• gcina isisindo esinempilo, eduze ne-BMI ejwayelekile;
• ukungabhemi, noma ukuyeka ukubhema;
• uphuze utshwala ngokulinganisela.

I-Hypertriglyceridemia ikhonjwa ngesikhathi sokuhlolwa kwe-lipid. Lokhu kuhlolwa kwegazi kukala amazinga ahlukene e-lipid kufaka phakathi izinga le-triglycerides (triglyceridemia).

Ukwelashwa kwe-hypertriglyceridemia kuncike enkambweni yayo, ubunzima bayo kanye nemiphumela yephrofayili ye-lipid.

Ukwehlisa i-triglyceridemia ephakeme kakhulu, kuyalulekwa ukuthi usebenzise indlela yokuphila enempilo ngokudla okunomsoco kanye nokwenza umkhuba wokuzivocavoca umzimba njalo.

Ngokuya ngohlobo lwe-hypertriglyceridemia, ukwelashwa okuningana kungabekwa. Ukuthatha ama-fibrate, ama-statins noma i-omega 3 fatty acids ngokwesibonelo kunganconywa.