eCayenne (I-Capsicum frutescens). I-US Food and Drug Administration (FDA) igunyaze ukusetshenziswa kokhilimu, izinto zokuthambisa, namafutha okugcoba enziwe nge-capsaicin (noma i-capsicin), isakhi esisebenzayo e-cayenne, ukuze kudambise ubuhlungu obubangelwaI-osteoarthritis. Izincomo zomhlaba wonke zincoma ukusetshenziswa kwasendaweni kwe-capsaicin⁵, ikakhulukazi i-osteoarthritis yamadolo.

Isikali

Faka isicelo ezindaweni ezithintekile, kuze kube izikhathi ezi-4 ngosuku, ukhilimu, amafutha okugcoba noma amafutha aqukethe i-capsaicin engu-0,025% kuya ku-0,075%. Ngokuvamile kuthatha izinsuku ezifika kweziyi-14 zokwelashwa ngaphambi kokuba kuzwakale umphumela ophelele wokwelapha. Qaphela, ukuzwa okuvuthayo kungase kuzwakale ngesikhathi sokufaka isicelo.

I-Glucosamine

I-Glucosamine ibamba iqhaza elibalulekile ekugcineni ubuqotho boqwanga lwabo bonke amalunga omzimba. Umzimba ukhiqiza ngokwemvelo. Izifundo eziningi zenziwe i-glucosamine sulfate.

 Nciphisa ubuhlungu obuhlangene (i-osteoarthritis emnene noma elinganiselayo). Ngaphandle kokuphikisana okuthile, iningi locwaningo kuze kube manje likhombisa ukuthi i-glucosamine iqeda, okungenani kancane, izimpawu ze-osteoarthritis emnene noma elinganiselayo (bona ishidi lethu leqiniso le-glucosamine). Iningi lezifundo ligxile kokuidolo i-osteoarthritis, abanye kufayela le-i-hip osteoarthritis.

 Nciphisa ukuqhubeka kwe-osteoarthritis. Iziphetho zezilingo zomtholampilo zesikhathi eside ezi-2 (iminyaka emi-3 lilinye, izifundo ezingama-414 sezizonke)^13-16 bonisa ukuthi isenzo se-glucosamine, ngaphezu kwemiphumela yayo ezimpawu, singasiza ekubambezeleni ukuqhubeka kwesifo. Inzuzo ngaphezu kwe-NSAID, evame ukusheshisa ukuqhubeka kwe-osteoarthritis.

Isikali. Thatha u-1 mg se i-glucosamine sulfate, kumthamo owodwa noma ngaphezulu, ngenkathi udla. Vumela amasonto amabili kuya kwayisithupha ukuthi isengezo sikhombise imiphumela yaso ephelele.

 Chondroitin. Njenge-glucosamine, i-chondroitin iyisakhi esibalulekile uqwanga futhi ngokwemvelo ikhiqizwa ngumzimba. Iningi locwaningo lwenziwe ngemikhiqizo enelungelo lobunikazi ehlanzeke kakhulu (i-Condrosulf®, Structum®, isibonelo). I-meta-analysis eminingi, ukubuyekezwa kanye nokuhlolwa komtholampilo kuphetha ngokuthi iyasebenza ukukhulula izimpawu i-osteoarthritis ethambile kuya kwemaphakathi kanye yehlisa ijubane ukuvela kwayo. Njenge-glucosamine, lokhu kuyinzuzo ngaphezu kwama-NSAID, avame ukusheshisa ukuqhubeka kwe-osteoarthritis. IChondroitin nayo ingundabuzekwayo. Xhumana nefayela lethu leChondroitin ukuze ufunde kabanzi ngezifundo ezenziwe kanye nokukhetha phakathi kweglucosamine ne-chondroitin.

Isikali

Thatha i-800 mg iye ku-1 mg ngosuku lwe-chondroitin, kumthamo owodwa noma ngaphezulu. Kuthatha amaviki angama-200 kuye kwayi-2 ukuze kuzwakale ngokuphelele.

 Same. I-SAMe (ye-S-Adenosyl-L-Methionine) ihlanganiswa ngumzimba kusuka kumaprotheni ekudleni. Isetshenziswa njengesengezo, kufakazelwe ukwelapha i-osteoarthritis²⁷. Imiphumela yezifundo ikhombise ukuthi ibisebenza njengemithi ejwayelekile yokulwa nokuvuvukala ngaphandle kwemiphumela emibi futhi iphephile.^28-31 .

Kodwa-ke, ukuhlaziywa kwe-meta okushicilelwe ngo-2009 kwehlisa ukusebenza nokuphepha kwe-S-adenosylmethionine. Ngokusho kwababhali bayo, izifundo ezimbalwa zinobuthakathaka bendlela kanye nenani elinganele labahlanganyeli. Baphetha ngokuthi umphumela we-analgesic we-SAMe (1 mg ngosuku) unesizotha⁸⁰.

Isikali

Thatha ama-400 mg izikhathi ezi-3 ngosuku amasonto ama-3 bese wehlisa umthamo wansuku zonke ube ngu-200 mg izikhathi ezi-2 ngosuku.

esasizizwa

Nakuba kungase kuthathe izinsuku ezimbalwa ukubonisa izinzuzo, kungathatha amaviki angu-5 ukuze ukwelashwa kusebenze ngokugcwele. Bheka ifayela lethu le-SAMe ukuze uthole imininingwane eyengeziwe.

 uzipho zikaDeveli (I-Harpagophytum procumbens). Impande kaDeveli yezipho ikhonjisiwe ukunciphisa ukuvuvukala. Ngaphandle kokubhuka mayelana nendlela yezifundo ezithile⁷⁹, imiphumela yezilingo eziningana zomtholampilo, noma ngaphandle kweqembu le-placebo, ikhombisa ukuthi impande kaDeveli yezinzipho ingathuthukisa ukuhamba futhi ikhulule kakhulu ubuhlungu^{35, 36,81-83}.

Isikali

Imithamo ingahluka kuye ngohlobo lokukhishwa. Landela imiyalelo yomkhiqizi. Kunconywa ukuthi ulandele ukwelashwa okungenani izinyanga ezi-2 noma ezi-3 ukuze usebenzise ngokugcwele imiphumela yako.

 I-Phytodolor®. Lo muthi wamakhambi ojwayelekile, othengiswa eYurophu njenge-tincture okufanele uthathwe ngaphakathi, uqukethe i-aspen ethuthumelayo (abantu), umlotha waseYurophu (I-Fraxinus excelsior) kanye ne-goldenrod (I-Solidago virgaurea) ngesilinganiso esingu-3: 1: 1. Lo mkhiqizo ungasebenza kangcono kune-placebo ekwehliseni izinhlungu, ukwandisa ukuhamba nokunciphisa ukusetshenziswa kwezidakamizwa ezingezona ukuvuvukala.^32-34 .

 I-Acupuncture. Izilingo eziningana zemitholampilo zihlolisise ukusebenza kwe-acupuncture kubuhlungu obuhambisana ne-osteoarthritis. Ukuhlaziywa kwe-meta okushicilelwe ngo-2007 futhi okubandakanya abantu abangaphezu kwabangu-1 baphetha ngokuthi ukutshopa kunganciphisa ubuhlungu nokukhubazeka okuhambisana ne-osteoarthritis⁵⁹. Kodwa-ke, ezinye izivivinyo zikhombisile ukuthi i-sham acupuncture nayo ingasebenza. Noma kunjalo, izincomo zomhlaba jikelele ekuphathweni kwe-osteoarthritis yamadolo nesinqe⁵ qaphela ukutshopa njengethuluzi eliphumelelayo lokuqeda izinhlungu.

 Hydrotherapy. Imiphumela yokuhlolwa okuhlukahlukene kwemitholampilo ibonisa ukuthi ukwelapha nge-hydrotherapy ngezindlela ezahlukene (i-spa, okugeza kusetshenziswa izinhlobo ezahlukene zamanzi, njll.) kungathuthukisa izinga lempilo yabantu abane-osteoarthritis, ngokwandisa ububanzi bokunyakaza. nokunciphisa ubuhlungu^49-54 . Ukubuyekezwa okuhlelekile okushicilelwe ngo-2009, okuhlanganisa izilingo ezingu-9 kanye neziguli ezingaba ngu-500, kuphetha ngokuthi i-balneotherapy iyasebenza esikhathini esifushane nesikhathi eside ebuhlungu obuhambisana ne-osteoarthritis yamadolo.⁴⁵.

 isixazululi nkinga yehadiwe nezinsiza. Kunezifundo ezimbalwa ezishicilelwe ekusebenzeni kwe-homeopathy ekwehliseni ubuhlungu nezimpawu ze-osteoarthritis. Ababhali bokubukeza okuhlelekile bakholelwa ukuthi i-homeopathy ingaba yindlela ewusizo yokwelapha i-osteoarthritis kodwa kudingeka izifundo eziningi ukuze kuqinisekiswe.⁴⁸. Bheka ishidi le-Homeopathy.

 Ukwatapheya nesoya akunakuphikiswa. Izinto ezikhishwe kukwatapheya nesoya - ingxenye engatholakali yamafutha azo - zingase zibe usizo kubantu abane-osteoarthritis yamadolo noma inqulu. Ngokusekelwe ezifundweni ezingu-4 zomtholampilo nge-placebo^37-41 , lezi zinto zisiza ukwenza ngcono ukusebenza kwamalunga nokunciphisa izinhlungu kanye nesidingo semithi elwa nokuvuvukala, ngaphandle kwemiphumela emibi. Njengamanje, ama-avocado kanye nama-soy angenakuphikiswa athengiswa eFrance kepha hhayi eCanada.

 I-Magnetotherapy. Ucwaningo oluningana luye lwahlola imiphumela ye-magnetotherapy, esetshenziswa kusetshenziswa izibuthe ezimile noma amadivaysi akhipha amasimu kagesi (EMF), ekwelapheni i-osteoarthritis futhi ikakhulukazi leyo yamadolo.^65-68 . IMagnetotherapy izokwehlisa ubuhlungu ngendlela enesizotha. Ngo-2009, ukubuyekezwa okubandakanya izifundo eziyi-9 neziguli ezingama-483 ezine-osteoarthritis yamadolo kwaphetha ngokuthi i-magnetotherapy iyindlela ehambisanayo ethokozisayo yokwenza ngcono ikhono lokusebenza futhi lula imisebenzi nsuku zonke⁵⁸.

 Ama-Leeches. Ucwaningo lomshayeli⁵⁵ kanye nokuhlolwa komtholampilo okungahleliwe okungu-2^{56, I-57} olwenziwa eJalimane lubonisa ukuthi ukusebenzisa iminyundu edolweni nge-osteoarthritis kungadambisa izinhlungu, ukuqina kokumelana nokunciphisa ezinye izimpawu. Ama-leeches ngokwesiko asetshenziswa ekwelapheni izinhlungu kusukela e-Antiquity abese eshiywa maphakathi nekhulu lesi-XNUMX.^e ikhulu leminyaka. Kodwa-ke, zisasetshenziswa kakhulu emithini yendabuko e-Asia, e-Afrika nasemazweni ama-Arab.

 Umnyezane omhlophe (I-Salix alba). Ukukhishwa kwe-willow white bark kuthiwa kusebenza kakhulu kune-placebo ekwehliseni ubuhlungu bamalunga obubangelwa yi-osteoarthritis. Kodwa-ke, esivivinyweni sababambiqhaza abayi-127 abane-osteoarthritis yamadolo noma inqulu, lezi zikhishwe bezingasebenzi kakhulu kunomuthi olwa nokuvuvukala (i-diclofenac).⁷⁴.

 Yoga. Imiphumela evela ekuhlolweni kwemitholampilo ezifundweni ezinempilo nakubantu abanezinkinga ezahlukahlukene zemisipha^{69, I-70} kwembula ukuthi umkhuba we-yoga ungasiza ekuthuthukiseni izici eziningana zalezi zimo, kufaka phakathi i-osteoarthritis yezandla⁷¹ namadolo⁷² kanye nesifo samathambo⁷³.

 Ukugqugquzela kagesi okudlulayo (TENS). Le nqubo isebenzisa idivayisi eyenza amandla kagesi aphansi, adluliselwe ezinzwa ngama-electrode abekwe esikhumbeni. Ukubuyekezwa kwezifundo ezanyatheliswa ngo-2000 kuphakamise ukuthi i-neurostimulation kagesi ye-transcutaneous ingaholela ekunciphiseni ubuhlungu be-knee osteoarthritis.⁴⁴. Kodwa-ke, ngo-2009, isibuyekezo esanyatheliswa yiqembu elifanayo labacwaningi, kuhlanganise nezilingo ezintsha, saphetha ngokuthi ukuphumelela kwale ndlela kwakungeke kuqinisekiswe nge-osteoarthritis yamadolo.⁴⁷.

 Abafakaza. Imininingwane ye-Epidemiological ikhombisa ukuthi ezindaweni lapho i-boron intake ingu-1 mg noma ngaphansi ngosuku, imvamisa yezinkinga zesifo samathambo iphakeme kakhulu (ama-20% kuye kuma-70%) kunezindawo lapho ukudla kwansuku zonke kuphakathi kuka-3 mg no-10 mg ngosuku ( 0% kuya ku-10%)³. Ucwaningo olulodwa lomtholampilo olusukela ngo-1990 futhi olubandakanya izihloko ezingama-20 lushicilelwe ngomphumela we-boron ku-osteoarthritis: ababambiqhaza baphawule ukuthuthuka okuncane esimweni sabo ngemuva kokuthatha u-6 mg ngosuku lwe-boron, amasonto ayi-8⁴.

 Boswellie (I-Boswellia serrata). I-Boswellia, izakhiwo zayo ezilwa nokuvuvukala eziboniswe ku-vitro nasezilwaneni, zingasiza ekwelapheni i-osteoarthritis. Ngempela, izifundo eziningana zeziguli ezine-osteoarthritis yamadolo zibonise imiphumela emihle.^42,43,61. Nokho, kusenedatha embalwa kakhulu ukuphakamisa umthamo.

 I-Collagen. I-Collagen iqinisekisa ukuhlangana, ukuqina nokuvuselelwa kwezicubu eziningana (imisipha, izicubu ezixhuma, imigqa, njll.). Izifundo ezihlolisise ukusebenza kwezithako ze-collagen zokuqeda i-osteoarthritis bezingakaqedi^75-77 . Ucwaningo lwamuva nje luthole ukukhululeka kobuhlungu obuncane⁷⁸. Idatha ye-in vitro iphakamisa ukuthi ukuthatha izithasiselo ezinjalo kungasiza ukujoyina okuthintekile ngokukhuthaza ukukhiqizwa kwe-collagen.

amanothi. Abacwaningi abaningi basebenzise umthamo we-10 g we-collagen hydrolyzate ngosuku. Amaphilisi namaphilisi atholakalayo ukuze athengiselwe ahlinzeka ngo-1g kuya ku-2g ngosuku.

 I-Tai chi. Ukuhlolwa komtholampilo kwenziwa kwabesifazane abangama-43 abangaphezu kweminyaka engama-55 abane-osteoarthritis⁶³. Bazilolonga i-tai chi masonto onke amaviki angu-12, noma babeyingxenye yeqembu lokulawula. Kube nezinguquko ezinhle ekuboneni ubuhlungu, ukuqina okuhlangene, ibhalansi namandla emisipha yesisu kwabesifazane abenza i-tai chi. Ngokusho kokubuyekezwa okuhlelekile okushicilelwe ku-2008, imiphumela iyathembisa kodwa ukuhlolwa okwengeziwe kwemitholampilo kuyodingeka ukuze kuqinisekiswe ukusebenza kahle kwe-tai chi.⁶⁰.

 Cassis (Izintambo nigrum). I-ESCOP ibona ukusetshenziswa kwezokwelapha kwamaqabunga e-blackcurrant (psn) njengokwelashwa okunciphisayo kwezifo ze-rheumatic. Inhlangano ikhombe inani elikhulu kakhulu lezifundo vivo ebonisa izakhiwo ezilwa nokuvuvukala zamaqabunga ukuze ziqaphele ngokusemthethweni lokhu kusetshenziswa okusungulwe isiko.

Isikali

Faka u-5 g kuye ku-12 g wamaqabunga omisiwe ku-250 ml wamanzi abilayo imizuzu eyi-15. Thatha izinkomishi ezi-2 ngosuku ngalokhu ukumnika, noma uthathe u-5 ml wokukhishwa ketshezi (1: 1), izikhathi ezimbili ngosuku, ngaphambi kokudla.

 Izitshalo ezihlukahlukene ziye zasetshenziswa ngokwesiko ukwelapha abantu abane-osteoarthritis: i-turmeric (psn) (I-Curcuma longai-ginger rhizomes (psn) (Zinziber officinalis) kanye nemfiva (I-Tanacetum parthenium).

 I-Massage Therapy. Izikhathi ze-massotherapy zifaka isandla esimweni senhlalakahle evamile kanye nokuphumula kwemisipha kanye nezinzwa. Iphinde ithuthukise ukujikeleza kwegazi kanye ne-lymphatic. Yingakho abanye ochwepheshe bencoma ukusetshenziswa kwayo ngabantu abane-osteoarthritis⁶⁴.