Izifo zemvubelo zikhula ikakhulukazi kubantu abanamasosha omzimba abuthakathaka. Kulezi zimo lapho ziyingozi kakhulu futhi zingase zingcolise umzimba wonke.

Ngakho-ke, abantu abasengozini enkulu yokutheleleka ngemvubelo enkulu yilaba:

• izingane ezizalwa ngaphambi kwesikhathi;
• abadala;
• abantu abanenkinga yokuzivikela komzimba (okulandela ukutheleleka nge-HIV, ukufakelwa isitho somzimba, i-chemo noma i-radiotherapy, ukuthatha izidakamizwa ezivimbela ukuzivikela komzimba noma i-corticosteroids yedosi ephezulu, njll.).

La ukukhulelwa futhi sikashukela nazo ziyizici ezithanda ukutheleleka kweyeast. Ukuthathakwemithi elwa namagciwane, ngokungalingani kwezitshalo zebhaktheriya ezigayayo, zingakhuthaza ukugcwala kwesikhunta esingapheli.