The ama-antibodies e-antithyroid (AAT) zingamasosha omzimba angavamile (autoantibodies) ahlasela yegilo ndlala.

Zivela ikakhulukazi uma kwenzeka isifo se-autoimmune yegilo.

Kunezinhlobo eziningana ze-AAT, ezihlose izingxenye ezahlukene ze-thyroid, kuhlanganise:

• i-anti-thyroperoxidase antibody (anti-TPO)
• anti-thyroglobulin (anti-TG) amasosha omzimba
• ama-anti-TSH receptor antibodies
• anti-T3 kanye ne-anti-T4 amasosha omzimba

I-AAT idonswa ikakhulukazi uma kwenzeka izimpawu zokungasebenzi kahle kwegilo, kodwa futhi nasekuhlolweniukungazali (ukuphuphunyelwa yizisu okuphindaphindiwe) noma ekulandeleni abesifazane abakhulelwe abaye babhekana nesifo se-thyroid. Ukuhlaziywa kwabo okuvamile kuyasiza ekuqapheni izifo ze-thyroid autoimmune.

Umthamo we-AAT wenziwa ngu-a isampula yegazi i-venous, imvamisa ekujuleni kwendololwane. Imiphumela iyahlukahluka kakhulu kusuka kulabhorethri yokuhlaziya eyodwa kuya kwenye, futhi kungase kudingeke izilinganiso ezimbalwa. Akudingekile ukuba ube esiswini esingenalutho ngaphambi kwesampula.

Ukuhlolwa kwehomoni yegilo (T3 kanye ne-T4) kungenziwa ngesikhathi esifanayo.

Ukuba khona kwe-AAT, ikakhulukazi ngamanani amancane, akuhambisani njalo nezimpawu.

Uma amazinga aphezulu ngokungavamile (ikakhulukazi i-anti-TPO), ngokuvamile kusho ukuthi kukhona ukungasebenzi kahle kwegilo. Udokotela kuphela ongahumusha imiphumela futhi akunikeze ukuxilongwa.

Ezinye izifo ze-autoimmune ze-thyroid zihlanganisa:

• Isifo sikaHashimoto
• i-thyroiditis yentsha
• Isifo samathuna
• i-postpartum thyroiditis (imvamisa ephakeme kakhulu ezinyangeni eziyisi-6 kuya kweziyisi-8 ngemuva kokubeletha)

Ukukhulelwa, ezinye izinhlobo zomdlavuza (i-thyroid), ukukhubazeka okuthile komzimba kungase kuhambisane nokwanda kwe-AAT.