Lezi zimpawu, ezibangelwa ukufa kwama-neurons engxenyeni eyodwa yobuchopho, ngokuvamile zivela nangaphambi kokuba kube nezinkinga zenkumbulo.
Abacwaningi base-Indiana University School of Medicine (USA) sebeveze okokuqala indlela yamangqamuzana engaphansi kwezimpawu ze-neuropsychiatric ezivame ukwandulela ukwehla kobuhlakani besifo i-Alzheimer's. Sikhuluma ngokulahlekelwa ugqozi, ukunganaki, ukukhathazeka, ukuguquguquka kwemizwa kungazelelwe kanye nokwanda kokucasuka.
Ososayensi bagxile ku-nucleus accumbens, isifunda sobuchopho esidlala indima ebalulekile ohlelweni lokuvuza. Kusuka ku-nucleus accumbens ukuthi ukusabela kolwazi olushukumisayo kuncike.
Abacwaningi bathole ukuthi iziguli ze-Alzheimer zinama-receptors ku-nucleus accumbens avumela i-calcium ukuthi ingene kuma-neurons. Imvamisa, akufanele kube nama-receptor anjalo ku-nucleus accumbens. Ukweqile kwe-calcium kuholela ekufeni kwama-neurons kanye nokulahlekelwa ukuxhumana kwe-synaptic phakathi kwabo, okubangela izimpawu ze-neuropsychiatric.
Ngokusekelwe kulokhu, ososayensi basikisela ukuthi ukuvinjwa okuhlosiwe kwama-calcium receptors ku-nucleus accumbens kungase kuvimbele noma kubambezele ukuqala kwesifo i-Alzheimer's.
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