Ezimweni eziningi, akukho ukwelashwa okuboniswayo. Ukungenelela okubaluleke kakhulu ukuhlonza kanye gwema okunye ukuchayeka ukuhola. Lokhu kungase kudinge ukuhlolwa kwekhaya kochwepheshe. Ukulandelela kwezokwelapha ngokuvamile kwenziwa njalo ezinyangeni ezi-3 kuya kweziyisi-6.

Uma kwenzeka'ubuthi obunzima obukhulu, ama-chelating agents, njenge ukunqotshwa orI-EDTA (ethylenediaminotetraacetic acid). Zijovwa emithanjeni lapho zibopha khona ama-molecule aholayo egazini bese zikhishwa emchamweni. Zehlisa izinga lomthofu wegazi ngo-40% kuya ku-50%¹. Inani lemithi yokwelapha lincike ebucayini bobuthi. Nge-EDTA, ukwelashwa kuthatha isilinganiso esiyizinsuku ezi-5. Akufanele kunwetshwe isikhathi eside ngokungadingekile ngoba i-agent ye-chelating iphinde ibophe kumaminerali anenzuzo emzimbeni, njengensimbi ne-zinc.

Kumele kuqashelwe ukuthi i-chelation ingabandakanya izingozi kubalulekile ngoba umthofu ubuyiselwa ekuhambeni emzimbeni¹⁹. Ngaphezu kwalokho, ukungezwani komzimba kungenzeka. Zimbalwa izifundo eziye zahlola ukusebenza kwalokhu kwelashwa ekwehliseni izimpawu ezisheshayo kanye nokuvimbela imiphumela yesikhathi eside yobuthi bomthofu. Isinqumo sokuphendukela kulolu hlobo lokwelashwa kufanele ngaso sonke isikhathi senziwe ngokuxoxisana nodokotela onolwazi kulo mkhakha.

Ngesikhathi esifanayo, udokotela uncoma a ukudla enempilo futhi enomsoco futhi uma kunesidingo izithasiselo i-calcium noma insimbi.