Okuqukethwe
Iphilisi liyindlela eyinhloko yokuvimbela inzalo kwabesifazane baseFrance. Izivimbela-nzalo zomlomo ezihlanganisiwe (COCs) ezibizwa ngokuthi amaphilisi e-estrogen-progestogen noma amaphilisi ahlanganisiwe yizona ezisetshenziswa kakhulu. Aqukethe kokubili i-estrogen ne-progestin. I-estrogen esetshenziswa kakhulu i-ethinyl estradiol (ephuma ku-estradiol). Iwuhlobo lwe-progestin olunquma ukukhiqizwa kwephilisi. Ama-platelet ayizigidi ezingu-66 wezivimbela-nzalo zomlomo ezihlanganisiwe (COC), zonke izizukulwane zihlangene, zathengiswa e-France ngo-2011. Qaphela: wonke amaphilisi esizukulwane sesibili abuyiselwa ngo-2, kuyilapho angaphansi kwesigamu salawo esizukulwane sesi-2012 futhi asikho isizukulwane sesine esingamboziwe Umshwalanse we mpilo.
Iphilisi lesizukulwane sokuqala
Amaphilisi esizukulwane sokuqala, adayiswa ngeminyaka yawo-1s, aqukethe umthamo ophezulu we-estrogen. Le hormone yayisemsuka wemiphumela emibi eminingi: ukuvuvukala kwamabele, isicanucanu, i-migraines, ukuphazamiseka kwemithambo. Iphilisi elilodwa kuphela lalolu hlobo elithengiswayo namuhla eFrance.. Le yindawo ka Triella.
amaphilisi esizukulwane sesibili
Ayethengiswa kusukela ngo-1973. Lawa maphilisi aqukethe i-levonorgestrel noma i-norgestrel njenge-progestogen. Ukusetshenziswa kwalawa mahomoni kwenza kwaba nokwenzeka ukwehlisa amazinga e-ethinyl estradiol futhi ngaleyo ndlela kwehle imiphumela engemihle abesifazane ababekhononda ngayo. Cishe owesifazane oyedwa kwababili uthatha iphilisi lesizukulwane sesibili phakathi kwalabo abasebenzisa izivimbela-nzalo zomlomo ezihlanganisiwe (COCs).
Amaphilisi esizukulwane sesi-3 nesesine
Amaphilisi amasha avele ngo-1984. Imithi yokuvimbela inzalo yesizukulwane sesithathu iqukethe izinhlobo ezahlukene ze-progestin: i-desogestrel, i-gestodene noma i-norgestimate. Okuhlukile kulawa maphilisi ukuthi anesilinganiso esiphansi se-estradiol, ukuze kuqhutshekwe nokunciphisa iziphazamiso, njengezinduna, ukuzuza isisindo, i-cholesterol. Ngaphezu kwalokho, abacwaningi baqaphele ukuthi ukugcwala okuphezulu kakhulu kwale hormone kungakhuthaza ukuvela kwe-venous thrombosis. Ngo-2001, amaphilisi esizukulwane sesine aqalwa emakethe. Aqukethe ama-progestin amasha (i-drospirenone, i-chlormadinone, i-dienogest, i-nomégestrol). Ucwaningo luye lwabonisa muva nje ukuthi amaphilisi esizukulwane sesi-3 nesesine anengozi ephindwe kabili ye-thromboembolism uma kuqhathaniswa namaphilisi esizukulwane sesibili.. Kulokhu, ama-progestin okukhulunywa ngawo. Kuze kube manje, sekufakwe izikhalazo eziyi-14 ngokumelene nelabhorethri ekhiqiza amaphilisi okuvimbela inzalo esizukulwane sesithathu nesesine. Kusukela ngo-3, amaphilisi okuvimbela inzalo esizukulwane sesithathu awasabuyiselwa.
Icala likaDiane 35 Isikhungo Sikazwelonke Sokuphepha Kwemikhiqizo Yezempilo (ANSM) simemezele ukumiswa kokugunyazwa ukumaketha (AMM) kwe-Diane 35 kanye namajenerikhi ayo. Lokhu kwelashwa kwe-acne ye-hormonal kwanqunywa njengendlela yokuvimbela inzalo. Ukufa okune "okubangelwa i-venous thrombosis" kuxhunywe ku-Diane 35. " |
Umthombo: I-Medicines Agency (ANSM)