THE insulin is a i-hormone ekhiqizwa ngokwemvelo yi- kwamanyikwe ekuphenduleni ukwanda kwezinga likashukela (glucose) egazini.

I-insulin inesenzo” i-hypoglycemia ", Okusho ukuthi, kwehlisa amazinga kashukela egazini, amazinga kashukela egazini. Eqinisweni, “itshela” amangqamuzana omzimba ukuba amunce i-glucose, esiza ukunciphisa izinga elijikelezayo egazini.

Inomphumela ophambene ne-glucagon, enye i-hormone ye-pancreatic ebangela ukwanda kwegazi glucose (umsebenzi we-hyperglycemia). I-insulin neglucagon zisebenza ndawonye ukuze kugcinwe amazinga kashukela egazini ezungeze i-1g/L ngaso sonke isikhathi.

Kusifo sikashukela, le bhalansi iyacasuka. I-insulin ikhiqizwa ngamanani amancane, futhi / noma amaseli awazweli kakhulu kuyo (ngakho-ke umphumela wayo uba buthaka).

Umthamo we-insulin egazini (i-insulinemia) ayisetshenziselwa ukuxilongwa noma ukuqapha isifo sikashukela (okusekelwe ekuhlaziyeni ushukela wegazi kanye ne-glycated hemoglobin).

Kodwa-ke, kungaba wusizo ukuhlola i-insulin egazini ukwazi amandla amanyikwe ukukhiqiza i-insulin (lokhu kungaba usizo kudokotela ezigabeni ezithile zesifo sikashukela).

Lokhu kuhlaziywa kungenziwa futhi uma kwenzeka i-hypoglycemia ephindaphindiwe. Kungasiza ekutholeni i-insulinoma (isimila esingajwayelekile se-endocrine pancreatic), ngokwesibonelo.

Ngokuvamile, udokotela ubeka "ukuhlolwa kwe-pancreatic", okusho ukuthi, ukuhlaziywa kwawo wonke amahomoni e-pancreatic kuhlanganise ne-insulin, i-C-peptide, i-proinsulins ne-glucagon.

I-insulin ihlolwa ngokuthathwa igazi elabhorethri yokuhlaziywa kwezokwelapha. Kubalulekile ukuzila ukudla ukuze uhlolwe igazi ukuze wazi umthamo “wesisekelo”.

Nokho, lokhu kuhlaziya ngokuvamile akwanele. Njengoba ukukhiqizwa kwe-insulin kuhluka kakhulu kumuntu ofanayo phakathi nosuku, umthamo owodwa kunzima ukuwuchaza. Ngakho-ke ukuhlolwa kwe-insulin kuvame ukwenziwa ngemva kokuhlolwa okuguquguqukayo okufana ne-oral hyperglycemia (OGTT), lapho isiguli sinikezwa isisombululo esimnandi kakhulu sokuphuza ukuze sibone ukuthi umzimba waso usabela kanjani.

Imiphumela izonikeza udokotela isiqondiso kuukwelashwa kwe-insulin, okungukuthi ukukhiqizwa kwe-insulin yi- kwamanyikwe, ikakhulukazi ngemva “kwesidlo” esimnandi.

Njengomhlahlandlela, esiswini esingenalutho, i-insulinemia imvamisa ingaphansi kwama-25 mIU / L (µIU / mL). Kuphakathi kwe-30 ne-230 mIU / L imizuzu engama-30 ngemuva kokuphathwa kweglucose.

Uma kwenzeka i-insulinoma, ngokwesibonelo, le mfihlo izoba phezulu ngokungavamile, ngokuqhubekayo, okuzobangela i-hypoglycemia ephindaphindiwe.

Udokotela kuphela ongahumusha imiphumela futhi akunikeze ukuxilongwa.